Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial) (Q58800590)

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scientific article published on 04 August 2018

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English	Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)	scientific article published on 04 August 2018

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16 April 2020

Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial) (English)

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16 April 2020

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based on heuristic

inferred from title

multicenter clinical trial

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based on heuristic

inferred from title

patent ductus arteriosus

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based on heuristic

inferred from title

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16 April 2020

Willem P de Boode

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16 April 2020

Koen P. Dijkman

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Koen P Dijkman

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Wes Onland

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Bart van Overmeire

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Peter Dijk

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Anton H L C van Kaam

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Elisabeth M W Kooi

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Eduardo Villamor

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André A Kroon

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Remco Visser

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Daniel C Vijlbrief

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Susanne M de Tollenaer

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David van Laere

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Anne-Britt Johansson

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16 April 2020

Catheline Hocq

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Alexandra Zecic

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Eddy Adang

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Rogier Donders

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Willem de Vries

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Arno F J van Heijst

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16 April 2020

Spontaneous Closure of Patent Ductus Arteriosus in Infants ≤1500 g.

1 reference

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30 November 2018

Trends in Patent Ductus Arteriosus Diagnosis and Management for Very Low Birth Weight Infants

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30 November 2018

Using benchmarking to identify inter-centre differences in persistent ductus arteriosus treatment: can we improve outcome?

1 reference

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30 November 2018

Prophylactic Indomethacin Compared with Delayed Conservative Management of the Patent Ductus Arteriosus in Extremely Preterm Infants: Effects on Neonatal Outcomes

1 reference

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30 November 2018

Changing Management of the Patent Ductus Arteriosus: Effect on Neonatal Outcomes and Resource Utilization

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30 November 2018

Comparative Effectiveness of Nonsteroidal Anti-inflammatory Drug Treatment vs No Treatment for Patent Ductus Arteriosus in Preterm Infants

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A conservative treatment of patent ductus arteriosus in very low birth weight infants.

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Trends and Outcomes of Patent Ductus Arteriosus Treatment in Very Preterm Infants in Canada

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Recent Advances in the Treatment of Preterm Newborn Infants with Patent Ductus Arteriosus

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Natural History of Patent Ductus Arteriosus in Very Low Birth Weight Infants after Discharge

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Diagnosis, Evaluation, and Management of Patent Ductus Arteriosus in Preterm Neonates

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Preterm patent ductus arteriosus: A continuing conundrum for the neonatologist?

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Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants

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What is new for patent ductus arteriosus management in premature infants in 2015?

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Hospital variation in medical and surgical treatment of patent ductus arteriosus

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Effects of therapeutic approach on the neonatal evolution of very low birth weight infants with patent ductus arteriosus

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Does targeted neonatal echocardiography affect hemodynamics and cerebral oxygenation in extremely preterm infants?

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Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates

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Budget impact analysis-principles of good practice: report of the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force

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Paracetamol to close the patent ductus arteriosus: From serendipity toward evidence based medicine.

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A randomised placebo-controlled trial of early treatment of the patent ductus arteriosus

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Comparison of oral paracetamol versus ibuprofen in premature infants with patent ductus arteriosus: a randomized controlled trial

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An Interesting Observation of PDA Closure with Oral Paracetamol in Preterm Neonates

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Paracetamol therapy for patent ductus arteriosus in premature infants: a chance before surgical ligation

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Paracetamol to induce ductus arteriosus closure: is it valid?

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Impact of oral versus intravenous ibuprofen on neurodevelopmental outcome: a randomized controlled parallel study

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Intravenous paracetamol treatment in the management of patent ductus arteriosus in extremely low birth weight infants

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A different first-choice drug in the medical management of patent ductus arteriosus: oral paracetamol

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Serum ibuprofen levels of extremely preterm infants treated prophylactically with oral ibuprofen to prevent patent ductus arteriosus

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Neurodevelopmental outcomes following two different treatment approaches (early ligation and selective ligation) for patent ductus arteriosus

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Treatment of patent ductus arteriosus and neonatal mortality/morbidities: adjustment for treatment selection bias

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Mortality and neonatal morbidity among infants 501 to 1500 grams from 2000 to 2009.

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Comparison of oral and intravenous Ibuprofen for medical closure of patent ductus arteriosus: which one is better?

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Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?

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Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis.

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Improved closure of patent ductus arteriosus with high doses of ibuprofen

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Patent ductus arteriosus: to treat or not to treat?

1 reference

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High-Dose Ibuprofen for Patent Ductus Arteriosus in Extremely Preterm Infants: A Randomized Controlled Study

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What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants?

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Learning to live with patency of the ductus arteriosus in preterm infants

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Efficacy and Safety of Oral Versus Intravenous Ibuprofen in Very Low Birth Weight Preterm Infants with Patent Ductus Arteriosus

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Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants

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Early surgical ligation versus a conservative approach for management of patent ductus arteriosus that fails to close after indomethacin treatment

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Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?

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Prophylaxis of symptomatic patent ductus arteriosus with oral ibuprofen in very low birth weight infants.

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Patent ductus arteriosus therapy: impact on neonatal and 18-month outcome

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A randomized, double-blind, placebo-controlled trial on intravenous ibuprofen L-lysine for the early closure of nonsymptomatic patent ductus arteriosus within 72 hours of birth in extremely low-birth-weight infants

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Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit

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Serious adverse events in academic critical care research

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Randomized trials in vulnerable populations

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Patent ductus arteriosus: lack of evidence for common treatments

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Towards rational management of the patent ductus arteriosus: the need for disease staging

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Treatment strategies to prevent or close a patent ductus arteriosus in preterm infants and outcomes

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Conservative treatment for patent ductus arteriosus in the preterm

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Definitions and diagnostic criteria for bronchopulmonary dysplasia

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Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less

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The International Classification of Retinopathy of Prematurity revisited

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Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management

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Comparison of clinical criteria with echocardiographic findings in diagnosing PDA in preterm infants

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30 November 2018

Dose-finding study of ibuprofen in patent ductus arteriosus using the continual reassessment method

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Cardiorespiratory stability during echocardiography in preterm infants

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Prophylactic ibuprofen versus placebo in very premature infants: a randomised, double-blind, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Patency of the ductus arteriosus in the premature infant: is it pathologic? Should it be treated?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Effect of early targeted indomethacin on the ductus arteriosus and blood flow to the upper body and brain in the preterm infant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Indomethacin for asymptomatic patent ductus arteriosus in preterm infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Indomethacin prophylaxis for patent ductus arteriosus (PDA) in infants with a birth weight of less than 1250 grams.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Randomized double-blind controlled trial comparing the effects of ibuprofen with indomethacin on cerebral hemodynamics in preterm infants with patent ductus arteriosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Effects of ibuprofen and indomethacin on the regional circulation in newborn piglets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Prophylactic indomethacin therapy in the first twenty-four hours of life for the prevention of patent ductus arteriosus in preterm infants treated prophylactically with surfactant in the delivery room

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Necrotizing enterocolitis: the search for a unifying pathogenic theory leading to prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Early closure of the patent ductus arteriosus in very low-birth-weight infants: a controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Indomethacin treatment for patent ductus arteriosus in very low birthweight infants: double blind trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Early closure of patent ductus arteriosus with indomethacin in preterm infants with idiopathic respiratory distress syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Indomethacin therapy on the first day of life in infants with very low birth weight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Failure of prophylactic indomethacin to improve the outcome of the very low birth weight infant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Early administration of indomethacin to preterm infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Early intravenous indomethacin prolongs respiratory support in very low birth weight infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Effects of early therapy with indomethacin on the manifestation of a persistent ductus arteriosus in extremely underweight premature infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6090763

30 November 2018

Effects of prostaglandins and indomethacin on cerebral blood flow and cerebral oxygen consumption of conscious newborn piglets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylactic treatment of asymptomatic patent ductus arteriosus in premature infants with respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of symptomatic patent ductus arteriosus with a single dose of indomethacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The silent ductus: its precursors and its aftermath

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of indomethacin in premature infants with patent ductus arteriosus: Results of a national collaborative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled trial of intravenous lyophilized indomethacin in the treatment of persistent ductus arteriosus in premature infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin treatment in patent ductus arteriosus. A double-blind study utilizing indomethacin plasma levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous indomethacin therapy in premature infants with persistent ductus arteriosus--a double-blind controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin for closure of patent ductus arteriosus in prematures

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early echocardiographic prediction of symptomatic patent ductus arteriosus in preterm infants undergoing mechanical ventilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A blinded comparison of clinical and echocardiographic evaluation of the preterm infant for patent ductus arteriosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin compromises hemodynamics during positive-pressure ventilation, independently of prostanoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of indomethacin and ibuprofen on mesenteric and renal blood flow in preterm infants with patent ductus arteriosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylactic ibuprofen therapy of patent ductus arteriosus in preterm infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between neuroimaging and neurological outcome in periventricular leukomalacia: diagnostic criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of a physiologic definition on bronchopulmonary dysplasia rates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral ibuprofen prophylaxis for symptomatic patent ductus arteriosus of prematurity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment to prevent patency of the ductus arteriosus: beneficial or harmful?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ductus arteriosus rarely requires treatment in infants > 1000 grams

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Budget impact analysis in economic evaluation: a proposal for a clearer definition

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ductal closure with paracetamol: a surprising new approach to patent ductus arteriosus treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Timing of patent ductus arteriosus treatment and respiratory outcome in premature infants: a double-blind randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of prophylactic indomethacin on renal and intestinal blood flows in premature infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is paracetamol safe and effective for ductus arteriosus closure?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paracetamol effectiveness, safety and blood level monitoring during patent ductus arteriosus closure: a case series

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural evolution of patent ductus arteriosus in the extremely preterm infant

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patent Ductus Arteriosus in Preterm Infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IMTA Productivity Cost Questionnaire (IPCQ)

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mandatory Closure Versus Nonintervention for Patent Ductus Arteriosus in Very Preterm Infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patent ductus arteriosus in premature infants: to treat or not to treat?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30077184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12887-018-1215-7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30077184%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12887-018-1215-7

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30077184%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30077184%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

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