Replacing a Surface Loop Endows Ribonuclease A with Angiogenic Activity (Q57961238)

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22 October 2019

title

Replacing a surface loop endows ribonuclease A with angiogenic activity (English)

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22 October 2019

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22 October 2019

M P Toscano

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22 October 2019

D M Nierengarten

series ordinal

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22 October 2019

J H Ha

series ordinal

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22 October 2019

R Auerbach

series ordinal

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22 October 2019

language of work or name

English

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publication date

1 July 1995

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Journal of Biological Chemistry

22 October 2019

published in

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22 October 2019

volume

270

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22 October 2019

issue

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22 October 2019

page(s)

17180-17184

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Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease

22 October 2019

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A hybrid of bovine pancreatic ribonuclease and human angiogenin: an external loop as a module controlling substrate specificity?

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Diffuse metastasized testicular teratoma and paraneoplastic thyreotoxicosis. Case report and literature review

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Deletion of the omega-loop in the active site of staphylococcal nuclease. 2. Effects on protein structure and dynamics.

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Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions

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Incorporation of a stabilizing Ca(2+)-binding loop into subtilisin BPN'

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Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11.

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Complete Amino-Acid Sequence of Actin of Rabbit Skeletal Muscle

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Angiogenesis in cancer, vascular, rheumatoid and other disease

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Calculation of protein extinction coefficients from amino acid sequence data

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Dual site model for the organogenic activity of angiogenin

21 January 2018

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A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis

21 January 2018

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Converting trypsin to chymotrypsin: the role of surface loops

21 January 2018

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An angiogenin-binding protein from endothelial cells.

21 January 2018

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Actin is a binding protein for angiogenin

21 January 2018

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Transfer of a beta-turn structure to a new protein context

21 January 2018

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Structural basis for the biological activities of bovine seminal ribonuclease

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Avascular and vascular phases of tumour growth in the chick embryo

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Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Tight-binding inhibition of angiogenin and ribonuclease A by placental ribonuclease inhibitor

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Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

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Angiogenesis in the mouse cornea

21 January 2018

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Stabilization of a reaction intermediate as a catalytic device: definition of the functional role of the flexible loop in triosephosphate isomerase.

21 January 2018

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Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis

21 January 2018

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Role of lysines in human angiogenin: chemical modification and site-directed mutagenesis

21 January 2018

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Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

21 January 2018

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21 January 2018

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Grafting of a calcium-binding loop of thermolysin to Bacillus subtilis neutral protease

21 January 2018

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Insertion in barnase of a loop sequence from ribonuclease T1. Investigating sequence and structure alignments by protein engineering.

21 January 2018

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Insertion of an elastase-binding loop into interleukin-1β

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.270.29.17180

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7615514%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

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