Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes (Q57833165)

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The phosphoinositide (PI) 3-kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

GSK-3: tricks of the trade for a multi-tasking kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

TCF transcription factors, mediators of Wnt-signaling in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The links between axin and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

β-catenin is a target for the ubiquitin–proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Glycogen and its Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The role of protein phosphatase-1 in insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Long-term treatment with novel glycogen synthase kinase-3 inhibitor improves glucose homeostasis in ob/ob mice: molecular characterization in liver and muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Lithium inhibits glycogen synthase kinase-3 by competition for magnesium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Lithium increases susceptibility of muscle glucose transport to stimulation by various agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Inhibition of glycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Short-term in vitro inhibition of glycogen synthase kinase 3 potentiates insulin signaling in type I skeletal muscle of Zucker Diabetic Fatty rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Chronic selective glycogen synthase kinase-3 inhibition enhances glucose disposal and muscle insulin action in prediabetic obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

PEPCK gene as model of inhibitory effects of insulin on gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

New connections in the regulation of PEPCK gene expression by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Different mechanisms are used by insulin to repress three genes that contain a homologous thymine-rich insulin response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: role of chronic hyperinsulinemia and hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Regulating insulin signaling and beta-cell function through IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.10.1265

Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

The glamour and gloom of glycogen synthase kinase-3

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Impaired muscle glycogen synthase in type 2 diabetes is associated with diminished phosphatidylinositol 3-kinase activation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

30 November 2018

Wnt signaling and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Glucose-6-Phosphatase Structure, Regulation, and Function: An Update

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

'Insulin-like' effects of lithium ion on isolated rat adipocytes. II. Specific activation of glycogen synthase.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Molecular cloning and expression of glycogen synthase kinase-3/factor A

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Multisite and hierarchal protein phosphorylation.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485462

Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3

30 November 2018

1 reference

12 December 2020

The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug

1 reference

12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

12 December 2020

Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice

1 reference

12 December 2020

Biosynthesis of glycogen from uridine diphosphate glucose

1 reference

12 December 2020

More marked stimulation by lithium than insulin of the glycogenic pathway in rat skeletal muscle

1 reference

12 December 2020