Loss of chromosome arms 3p and 9p and inactivation ofP16INK4a in normal epithelium of patients with primary lung cancer (Q57240046)

object named as

James G. Herman

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William H. Westra

object named as

William H. Westra

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author name string

Ot�via L. Caballero

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Daniel Cohen

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Qing Liu

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Julie Bonacum

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Peter White

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James Engles

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Robert Yochem

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Christoph Lengauer

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Jin Jen

Genes, Chromosomes and Cancer

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publication date

2001

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published in

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volume

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issue

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page(s)

119-125

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cites work

Molecular Detection of Tumor Cells in Bronchoalveolar Lavage Fluid From Patients With Early Stage Lung Cancer

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Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

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Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

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Clones and subclones in the lung cancer field.

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Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma

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Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers

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Role of the p16 tumor suppressor gene in cancer

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

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Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer

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Development of carcinoma of the lung as reflected in exfoliated cells.

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Molecular Damage in the Bronchial Epithelium of Current and Former Smokers

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Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma

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Rates of p16 (MTS1) mutations in primary tumors with 9p loss

21 January 2018

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7 January 2021

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

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7 January 2021

Mechanisms of p16INK4A inactivation in non small-cell lung cancers

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7 January 2021

The role of deletions at the FRA3B/FHIT locus in carcinogenesis.

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7 January 2021

Differential frequencies of p16(INK4a) promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers

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7 January 2021

Clonal genetic alterations in the lungs of current and former smokers

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7 January 2021

Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescencein situ hybridization

1 reference

7 January 2021

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

7 January 2021