The clinical implications of reduced viral fitness (Q57207415)

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English	The clinical implications of reduced viral fitness	article

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scholarly article

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Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

title

The Clinical Implications of Reduced Viral Fitness (English)

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stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

author

Robert M. Grant

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

author name string

Jason D. Barbour

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

publication date

1 April 2004

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

published in

Current infectious disease reports

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

volume

6

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stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

issue

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

page(s)

151-158

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

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Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo

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PubMed

reference URL

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12 December 2020

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Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215.

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PubMed

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12 December 2020

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Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection

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12 December 2020

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An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses

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12 December 2020

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Sustained CD4+ T cell response after virologic failure of protease inhibitor-based regimens in patients with human immunodeficiency virus infection

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12 December 2020

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Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.

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12 December 2020

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Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication

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12 December 2020

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Infection of the SCID-hu mouse by HIV-1

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12 December 2020

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Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda

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Selected sexual practices of San Francisco heterosexual men and risk of infection by the human immunodeficiency virus

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12 December 2020

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Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. North American HIV Working Party

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Genome and virulence determinants of high virulence community-acquired MRSA

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12 December 2020

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Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

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12 December 2020

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Antiretroviral-drug resistance among patients recently infected with HIV.

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12 December 2020

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AIDS as a zoonosis: scientific and public health implications

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12 December 2020

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Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level

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12 December 2020

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Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study

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12 December 2020

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Primary and recombinant HIV type 1 strains resistant to protease inhibitors are pathogenic in mature human lymphoid tissues

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.

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12 December 2020

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A randomized, controlled trial of indinavir, zidovudine, and lamivudine in adults with advanced human immunodeficiency virus type 1 infection and prior antiretroviral therapy

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12 December 2020

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12 December 2020

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Timing the ancestor of the HIV-1 pandemic strains

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12 December 2020

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Retracing the evolutionary pathways of human immunodeficiency virus type 1 resistance to protease inhibitors: virus fitness in the absence and in the presence of drug

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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inferred from PubMed ID database lookup

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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Protease inhibitor-resistant HIV-1 from patients with preserved CD4 cell counts is cytopathic in activated CD4 T lymphocytes.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

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12 December 2020

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Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental HIV infection of human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time trends in primary HIV-1 drug resistance among recently infected persons

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5'-end- and DNA 3'-end-directed RNase H activities

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Procedures for reliable estimation of viral fitness from time-series data.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selection

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15023278

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S11908-996-0012-X

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

PubMed publication ID

15023278

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15023278

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15023278%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 December 2019

 

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