Host-pathogen kinetics during influenza infection and coinfection: insights from predictive modeling (Q57164156)

12 December 2020

The microbiology of otitis media.

1 reference

12 December 2020

Some aspects of the pneumococcal carrier state.

1 reference

12 December 2020

Cellular resistance to induction of interferon

1 reference

12 December 2020

Inhibition of neutrophil lysosome-phagosome fusion associated with influenza virus infection in vitro. Role in depressed bactericidal activity

1 reference

12 December 2020

Interferons, Mx genes, and resistance to influenza virus

1 reference

12 December 2020

Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza

1 reference

12 December 2020

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection

1 reference

12 December 2020

Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense

1 reference

12 December 2020

Type I interferons keep activated T cells alive

1 reference

12 December 2020

Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria

1 reference

12 December 2020

In vitro growth profiles of respiratory syncytial virus in the presence of influenza virus

1 reference

12 December 2020

Neutrophil survival is markedly reduced by incubation with influenza virus and Streptococcus pneumoniae: role of respiratory burst

1 reference

12 December 2020

The prevention of pneumococcal disease in children

1 reference

12 December 2020

Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor

1 reference

12 December 2020

Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza.

1 reference

12 December 2020

Streptococcus pneumoniae colonisation: the key to pneumococcal disease

1 reference

12 December 2020

Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza

1 reference

12 December 2020

Influenza-associated hospitalizations in the United States

1 reference

12 December 2020

The host type I interferon response to viral and bacterial infections

1 reference

12 December 2020

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

1 reference

12 December 2020

Density-dependent decay in HIV-1 dynamics.

1 reference

12 December 2020

Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming

1 reference

12 December 2020

Anti-inflammatory properties of Type I interferons

1 reference

12 December 2020

Interactions between influenza and bacterial respiratory pathogens: implications for pandemic preparedness

1 reference

12 December 2020

Kinetics of influenza A virus infection in humans

1 reference

12 December 2020

Both influenza-induced neutrophil dysfunction and neutrophil-independent mechanisms contribute to increased susceptibility to a secondary Streptococcus pneumoniae infection

1 reference

12 December 2020

A dynamical model of human immune response to influenza A virus infection

1 reference

12 December 2020

Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo

1 reference

12 December 2020

Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

1 reference

12 December 2020

Neuraminidase inhibitor resistance in influenza: assessing the danger of its generation and spread

1 reference

12 December 2020

Type I interferons as anti-inflammatory mediators

1 reference

12 December 2020

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

1 reference

12 December 2020

Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice

1 reference

12 December 2020

Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection

1 reference

12 December 2020

A simple mathematical model helps to explain the immunodominance of CD8 T cells in influenza A virus infections

1 reference

12 December 2020

Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness

1 reference

12 December 2020

Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza

1 reference

12 December 2020

Mathematical modeling of viral kinetics under immune control during primary HIV-1 infection

1 reference

12 December 2020

Towards a quantitative understanding of the within-host dynamics of influenza A infections

1 reference

12 December 2020

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

1 reference

12 December 2020

An accurate two-phase approximate solution to an acute viral infection model

1 reference

12 December 2020

Impaired immune responses in the lungs of aged mice following influenza infection

1 reference

12 December 2020

Bacterial pathogens and death during the 1918 influenza pandemic

1 reference

12 December 2020

A systematic approach to virus-virus interactions.

1 reference

12 December 2020

Dynamics of influenza virus infection and pathology.

1 reference

12 December 2020

Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus

1 reference

12 December 2020

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

1 reference

12 December 2020

Neuraminidase inhibitors for treatment of human and avian strain influenza: A comparative modeling study.

1 reference

12 December 2020

Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling

1 reference

12 December 2020

Population Modeling of Influenza A/H1N1 Virus Kinetics and Symptom Dynamics

1 reference

12 December 2020

Influenza A virus infection kinetics: quantitative data and models

1 reference

12 December 2020

Design considerations in building in silico equivalents of common experimental influenza virus assays.

1 reference

12 December 2020

Mathematical model of a three-stage innate immune response to a pneumococcal lung infection

1 reference

12 December 2020

A review of mathematical models of influenza A infections within a host or cell culture: lessons learned and challenges ahead

1 reference

12 December 2020

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

1 reference

12 December 2020

Preventing and treating secondary bacterial infections with antiviral agents

1 reference

12 December 2020

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model

1 reference

12 December 2020

Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children

1 reference

12 December 2020

ON IDENTIFIABILITY OF NONLINEAR ODE MODELS AND APPLICATIONS IN VIRAL DYNAMICS.

1 reference

12 December 2020

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

1 reference

12 December 2020

Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses

1 reference

12 December 2020

Immune responses to influenza virus infection

1 reference

12 December 2020

Induction and evasion of type I interferon responses by influenza viruses

1 reference

12 December 2020

Impact of the 2009 influenza pandemic on pneumococcal pneumonia hospitalizations in the United States

1 reference

12 December 2020

Antivirals and resistance: influenza virus

1 reference

12 December 2020

Combination antiviral therapy for influenza: predictions from modeling of human infections

1 reference

12 December 2020

Interactions between Streptococcus pneumoniae and influenza virus: a mutually beneficial relationship?

1 reference

12 December 2020

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

1 reference

12 December 2020

Modeling within-host dynamics of influenza virus infection including immune responses

1 reference

12 December 2020

Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses.

1 reference

12 December 2020

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.

1 reference

12 December 2020

Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cells

1 reference

12 December 2020

Bacterial neuraminidase rescues influenza virus replication from inhibition by a neuraminidase inhibitor

1 reference

12 December 2020

Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalisation and mortality.

1 reference

12 December 2020

Newer influenza antivirals, biotherapeutics and combinations

1 reference

12 December 2020

Epidemiology of multiple respiratory viruses in childcare attendees

1 reference

12 December 2020

Assessing mathematical models of influenza infections using features of the immune response.

1 reference

12 December 2020

Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae

1 reference

12 December 2020

Reducing uncertainty in within-host parameter estimates of influenza infection by measuring both infectious and total viral load

1 reference

12 December 2020

Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections

1 reference

12 December 2020

Time and dose-dependent risk of pneumococcal pneumonia following influenza: a model for within-host interaction between influenza and Streptococcus pneumoniae

1 reference

12 December 2020

Immune dysfunction and bacterial coinfections following influenza

1 reference

12 December 2020

Modeling inoculum dose dependent patterns of acute virus infections.

1 reference

12 December 2020

Effects of aging on influenza virus infection dynamics.

1 reference

12 December 2020

Single, dual and multiple respiratory virus infections and risk of hospitalization and mortality.

1 reference

12 December 2020

The co-pathogenesis of influenza viruses with bacteria in the lung.

1 reference

12 December 2020

A mathematical model of intrahost pneumococcal pneumonia infection dynamics in murine strains.

1 reference

12 December 2020

Pretreatment of epithelial cells with live Streptococcus pneumoniae has no detectable effect on influenza A virus replication in vitro

1 reference

12 December 2020

Within-host influenza dynamics: a small-scale mathematical modeling approach.

1 reference

12 December 2020

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection

1 reference

12 December 2020

Secondary bacterial infections in influenza virus infection pathogenesis.

1 reference

12 December 2020

A large-scale immuno-epidemiological simulation of influenza A epidemics

1 reference

12 December 2020

Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization

1 reference

12 December 2020

Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8⁺ T cell response

1 reference

12 December 2020

Associations between co-detected respiratory viruses in children with acute respiratory infections.

1 reference

12 December 2020

Importance of bacterial replication and alveolar macrophage-independent clearance mechanisms during early lung infection with Streptococcus pneumoniae

1 reference

12 December 2020

Type I interferons in infectious disease

1 reference

12 December 2020

Community-acquired pneumonia requiring hospitalization among U.S. children

1 reference

12 December 2020

The immunology of influenza virus-associated bacterial pneumonia

1 reference

12 December 2020

Estimating influenza disease burden from population-based surveillance data in the United States

1 reference

12 December 2020

Regulation of antiviral T cell responses by type I interferons

1 reference

12 December 2020

The inflammatory response to influenza A virus (H1N1): An experimental and mathematical study

1 reference

12 December 2020

Alveolar macrophages and type I IFN in airway homeostasis and immunity

1 reference

12 December 2020

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

1 reference

12 December 2020

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice

1 reference

12 December 2020

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults

1 reference

12 December 2020

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

1 reference

12 December 2020

Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease

1 reference

12 December 2020

A Three-Tiered Study of Differences in Murine Intrahost Immune Response to Multiple Pneumococcal Strains

1 reference

12 December 2020

Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

1 reference

12 December 2020

Modeling Influenza Virus Infection: A Roadmap for Influenza Research

1 reference

12 December 2020

Enhanced growth of influenza A virus by coinfection with human parainfluenza virus type 2.

1 reference

12 December 2020

Human influenza viruses and CD8(+) T cell responses.

1 reference

12 December 2020

Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus.

1 reference

12 December 2020

Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

1 reference

12 December 2020

Coinfections of the Respiratory Tract: Viral Competition for Resources

1 reference

12 December 2020

The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis

1 reference

12 December 2020

Mathematical Model Reveals the Role of Memory CD8 T Cell Populations in Recall Responses to Influenza.

1 reference

12 December 2020

Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza

1 reference

12 December 2020

Influenza virus infection causes neutrophil dysfunction through reduced G-CSF production and an increased risk of secondary bacteria infection in the lung.

1 reference

12 December 2020

Quantifying the therapeutic requirements and potential for combination therapy to prevent bacterial coinfection during influenza.

1 reference

12 December 2020

Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host.

1 reference

12 December 2020

Hierarchical effects of pro-inflammatory cytokines on the post-influenza susceptibility to pneumococcal coinfection

1 reference

12 December 2020

Viral-bacterial interactions in the respiratory tract

1 reference

12 December 2020

A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

1 reference

12 December 2020

Analysis of Practical Identifiability of a Viral Infection Model

1 reference

12 December 2020

Intraseason waning of influenza vaccine protection: Evidence from the US Influenza Vaccine Effectiveness Network, 2011-12 through 2014-15.

1 reference

12 December 2020

On the Role of CD8+ T Cells in Determining Recovery Time from Influenza Virus Infection

1 reference

12 December 2020

Exploring virus release as a bottleneck for the spread of influenza A virus infection in vitro and the implications for antiviral therapy with neuraminidase inhibitors.

1 reference

12 December 2020

Discrete Dynamical Modeling of Influenza Virus Infection Suggests Age-Dependent Differences in Immunity

1 reference

12 December 2020

The Mechanisms for Within-Host Influenza Virus Control Affect Model-Based Assessment and Prediction of Antiviral Treatment

1 reference

12 December 2020

A pharmacologically immunosuppressed mouse model for assessing influenza B virus pathogenicity and oseltamivir treatment

1 reference

12 December 2020

The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza

1 reference

12 December 2020

The etiology and impact of co-infections in children hospitalized with community-acquired pneumonia

1 reference

12 December 2020

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection.

1 reference

12 December 2020

Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond

1 reference

12 December 2020

Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain

1 reference

12 December 2020

Influenza Virus Infection Model With Density Dependence Supports Biphasic Viral Decay

1 reference

12 December 2020

Host-pathogen kinetics during influenza infection and coinfection: insights from predictive modeling

1 reference

12 December 2020

Attenuation of Influenza A Virus Disease Severity by Viral Coinfection in a Mouse Model

1 reference

12 December 2020

Investigating Functional Roles for Positive Feedback and Cellular Heterogeneity in the Type I Interferon Response to Viral Infection

1 reference

12 December 2020