Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study (Q57035132)

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scientific article published on 3 October 2018

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English	Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study	scientific article published on 3 October 2018

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26 April 2020

Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study (English)

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26 April 2020

retinal ganglion cell

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1

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26 April 2020

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Ru Xiao

2

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26 April 2020

Jeffrey Bair

3

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26 April 2020

Fang Wang

4

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26 April 2020

Luk H Vandenberghe

5

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26 April 2020

Darlene Dartt

6

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26 April 2020

Petr Baranov

7

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26 April 2020

Yin Shan Eric Ng

8

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26 April 2020

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3 October 2018

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26 April 2020

Cell Death and Disease

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26 April 2020

9

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26 April 2020

10

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26 April 2020

1018

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26 April 2020

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1 October 2018

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6170416/fullTextXML

based on heuristic

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Diverse roles for VEGF-A in the nervous system

1 reference

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7 January 2021

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

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7 January 2021

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Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system

1 reference

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7 January 2021

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VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma

1 reference

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7 January 2021

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Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy

1 reference

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7 January 2021

based on heuristic

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Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

based on heuristic

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Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism

1 reference

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7 January 2021

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Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

based on heuristic

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The biology of VEGF and its receptors

1 reference

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7 January 2021

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VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

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Membrane-tethered ligands: tools for cell-autonomous pharmacological manipulation of biological circuits

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of a VEGF-VEGF receptor complex determined by electron microscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of VEGF isoforms in mouse during development and in the adult

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

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The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

1 reference

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Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

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AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells

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1 reference

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7 January 2021

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Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

based on heuristic

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Caspases in retinal ganglion cell death and axon regeneration.

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

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Mechanisms and regulation of endothelial VEGF receptor signalling.

1 reference

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BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons

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Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

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Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

7 January 2021

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VEGF: a critical player in neurodegeneration

1 reference

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7 January 2021

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Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-1049-0

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VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

1 reference

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KLF family members regulate intrinsic axon regeneration ability.

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Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration

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1 reference

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1 reference

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1 reference

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10.1038/S41419-018-1049-0

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30282966%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30282966%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30282966%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

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