Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis. (Q54517954)

30 May 2018

title

Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis. (English)

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30 May 2018

Kang-Yell Choi

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30 May 2018

author name string

Woo-Jeong Jeong

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30 May 2018

Juyong Yoon

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30 May 2018

Jong-Chan Park

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30 May 2018

Soung-Hoon Lee

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30 May 2018

Seung-Hoon Lee

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30 May 2018

Saluja Kaduwal

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Hoguen Kim

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Jong-Bok Yoon

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30 May 2018

publication date

10 April 2012

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30 May 2018

published in

Science Signaling

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volume

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issue

219

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page(s)

ra30

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Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

RAS oncogenes: weaving a tumorigenic web

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

The guanine nucleotide-binding switch in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Hyperactive Ras in developmental disorders and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Differential modification of Ras proteins by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Regulation of Ras localization by acylation enables a mode of intracellular signal propagation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Wnt/beta-catenin signaling in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

APC inhibits ERK pathway activation and cellular proliferation induced by RAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

MafA stability in pancreatic beta cells is regulated by glucose and is dependent on its constitutive phosphorylation at multiple sites by glycogen synthase kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Regulation of protein stability by GSK3 mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Emerging roles of ATF2 and the dynamic AP1 network in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Biology of the adenomatous polyposis coli tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Mouse models of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

The candidate oncogene ZNF217 is frequently amplified in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Differential regulation and properties of MAPKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002242

10.1126/SCISIGNAL.2002242

21 January 2018

Identifiers

DOI

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30 May 2018

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30 May 2018