FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3. (Q54375099)

29 May 2018

title

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3. (English)

1 reference

29 May 2018

main subject

spinocerebellar ataxia

1 reference

Thomas Klockgether

1 reference

29 May 2018

author name string

Julieta Araujo

1 reference

29 May 2018

Peter Breuer

1 reference

29 May 2018

Susanne Dieringer

1 reference

29 May 2018

Sybille Krauss

1 reference

29 May 2018

Stephanie Dorn

1 reference

29 May 2018

Katrin Zimmermann

1 reference

29 May 2018

Alexander Pfeifer

1 reference

29 May 2018

Ullrich Wuellner

1 reference

29 May 2018

Bernd O Evert

1 reference

29 May 2018

publication date

2 May 2011

1 reference

29 May 2018

published in

Human Molecular Genetics

1 reference

29 May 2018

volume

1 reference

29 May 2018

issue

1 reference

29 May 2018

page(s)

2928-2941

1 reference

29 May 2018

Trinucleotide Repeat Disorders

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Gene Expression Profiling in Ataxin-3 Expressing Cell Lines Reveals Distinct Effects of Normal and Mutant Ataxin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Proteotoxic stress increases nuclear localization of ataxin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Stressing the role of FoxO proteins in lifespan and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Mdm2 induces mono-ubiquitination of FOXO4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Poly-ubiquitin Binding by the Polyglutamine Disease Protein Ataxin-3 Links Its Normal Function to Protein Surveillance Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Oxidative stress: oxidants and antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Evidence of oxidant damage in Huntington's disease: translational strategies using antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Neurodegeneration. A glutamine-rich trail leads to transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Functional genomics and biochemical characterization of the C. elegans orthologue of the Machado-Joseph disease protein ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

Stable knockdown of CFTR establishes a role for the channel in P2Y receptor-stimulated anion secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR197

21 January 2018

Identifiers

DOI

10.1093/HMG/DDR197

1 reference

29 May 2018

1 reference

29 May 2018