Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine. (Q54216581)

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English	Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine. (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

author name string

Gschwendt M

1

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

Kittstein W

2

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

Marks F

3

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

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publication date

1 January 1994

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

1 reference

Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

338

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

1

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

85-88

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Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues

1 reference

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Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation

1 reference

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The tumour promoter okadaic acid inhibits reticulocyte-lysate protein synthesis by increasing the net phosphorylation of elongation factor 2.

1 reference

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21 January 2018

Functional properties of phosphorylated elongation factor 2

1 reference

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Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: stimulation of an elongation factor 2 phosphatase activity by TPA in vivo

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The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vit

1 reference

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Phosphorylation of elongation factor 2 during Ca(2+)-mediated secretion from rat parotid acini

1 reference

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Increased phosphorylation of elongation factor 2 during mitosis in transformed human amnion cells correlates with a decreased rate of protein synthesis

1 reference

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21 January 2018

Cyclosporin A inhibits phorbol ester-induced cellular proliferation and tumor promotion as well as phosphorylation of a 100-kd protein in mouse epidermis.

1 reference

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21 January 2018

Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin

1 reference

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21 January 2018

Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds

1 reference

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21 January 2018

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1 reference

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21 January 2018

Chelerythrine is a potent and specific inhibitor of protein kinase C.

1 reference

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Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

1 reference

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21 January 2018

Expression and partial characterization of rat protein kinase C-delta and protein kinase C-zeta in insect cells using recombinant baculovirus

1 reference

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Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain

1 reference

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21 January 2018

Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes

1 reference

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21 January 2018

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

1 reference

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21 January 2018

Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases

1 reference

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21 January 2018

Potent selective inhibitors of protein kinase C

1 reference

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Signalling targets for anticancer drug development

1 reference

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Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC

1 reference

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21 January 2018

Identifiers

10.1016/0014-5793(94)80121-5

1 reference

Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 May 2018

http://europepmc.org/abstract/MED/8307162

ResearchGate publication ID

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