The potassium channel opening action of pinacidil; studies using biochemical, ion flux and microelectrode techniques. (Q54122172)

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English	The potassium channel opening action of pinacidil; studies using biochemical, ion flux and microelectrode techniques.	scientific article

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Europe PubMed Central

PubMed publication ID

2848206

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25 May 2018

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http://europepmc.org/abstract/MED/2848206

title

The potassium channel opening action of pinacidil; studies using biochemical, ion flux and microelectrode techniques. (English)

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2848206

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25 May 2018

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J S Southerton

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1

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2848206

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A H Weston

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2

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2848206

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K M Bray

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3

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2848206

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http://europepmc.org/abstract/MED/2848206

D T Newgreen

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4

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2848206

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http://europepmc.org/abstract/MED/2848206

S G Taylor

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5

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2848206

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publication date

1 September 1988

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2848206

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http://europepmc.org/abstract/MED/2848206

published in

Naunyn-Schmiedeberg's Archives of Pharmacology

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PubMed publication ID

2848206

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25 May 2018

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http://europepmc.org/abstract/MED/2848206

volume

338

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PubMed publication ID

2848206

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25 May 2018

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http://europepmc.org/abstract/MED/2848206

issue

3

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PubMed publication ID

2848206

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25 May 2018

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http://europepmc.org/abstract/MED/2848206

page(s)

310-318

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2848206

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cites work

Evidence for two distinct calcium channels in rat vascular smooth muscle cells in short-term primary culture

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Systemic and coronary hemodynamic effects of pinacidil, a new antihypertensive agent, in awake dogs: comparison with hydralazine.

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Vasodilating actions of 2-nicotinamidoethyl nitrate on porcine and guinea-pig coronary arteries.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Comparison of rubidium-86 and potassium-42 fluxes in rat aorta

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12 December 2020

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Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate

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12 December 2020

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Immediate central and peripheral haemodynamic effects of a new vasodilating agent Pinacidil (P1134) in hypertensive man.

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12 December 2020

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The mechanism of action of Ba2+ and TEA on single Ca2+-activated K+ -channels in arterial and intestinal smooth muscle cell membranes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Vascular effects in dogs of pinacidil (P 1134), a novel vasoactive antihypertensive agent

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PubMed

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12 December 2020

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Recovery of contractile function in post-ischaemic reperfused myocardium of conscious dogs: influence of nicorandil, a new antianginal agent

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PubMed

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12 December 2020

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The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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BRL 34915, a novel antihypertensive agent: comparison of effects on blood pressure and other haemodynamic parameters with those of nifedipine in animal models

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Cardiovascular effects of a new coronary vasodilator N-(2-hydroxyethyl)nicotinamide nitrate (SG-75): comparison with nitroglycerin and diltiazem

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle

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PubMed

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12 December 2020

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Cyclic GMP as Possible Mediator of Coronary Arterial Relaxation by Nicorandil (SG-75)

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Similarities in the mechanism of action of two new vasodilator drugs: pinacidil and BRL 34915.

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12 December 2020

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Effects of pinacidil on serotonin-induced contractions and cyclic nucleotide levels in isolated rat aortae: comparison with nitroglycerin, minoxidil, and hydralazine.

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PubMed

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12 December 2020

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Characteristics of cromakalim-induced relaxations in the smooth muscle cells of guinea-pig mesenteric artery and vein

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PubMed

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12 December 2020

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Comparison of the effects of a new vasodilator pinacidil and nifedipine on isolated blood vessels

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PubMed

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12 December 2020

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Simultaneous long-term recording of the mechanical and intracellular electrical activity of smooth muscles

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

based on heuristic

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Vasodilatation induced by pinacidil in dogs. Comparison with hydralazine and nifedipine.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

retrieved

12 December 2020

based on heuristic

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Effects of 2-nicotinamidoethyl nitrate (nicorandil; SG-75) and its derivative on smooth muscle cells of the canine mesenteric artery

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Nicorandil attenuates myocardial acidosis during coronary occlusion in dogs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

based on heuristic

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The Distribution of Sodium, Potassium and Chloride in the Smooth Muscle of the Rat Portal Vein

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12 December 2020

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Effect of apamin on responses to BRL 34915, nicorandil and other relaxants in the guinea-pig taenia caeci

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PubMed

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12 December 2020

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The diverse effects of noradrenaline and other stimulants on 86Rb and 42K efflux in rabbit and guinea-pig arterial muscle

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PubMed

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12 December 2020

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Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea-pig hepatocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

based on heuristic

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Pharmacokinetics and distribution of the new antihypertensive agent pinacidil in rat, dog and man

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/2848206

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a new vasodilator, pinacidil (P 1134), on potassium, noradrenaline and serotonin induced contractions in rabbit vascular tissues

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

based on heuristic

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Synthesis and hypotensive activity of N-alkyl-N"-cyano-N'-pyridylguanidines

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Patch and whole-cell voltage clamp of single mammalian visceral and vascular smooth muscle cells

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PubMed

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12 December 2020

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N''-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine, monohydrate (P 1134): a new, potent vasodilator

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/2848206

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic characterization of pinacidil in rats. Comparison with hydralazine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/2848206

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/2848206

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/2848206

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12 December 2020

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Identifiers

DOI

10.1007/BF00173406

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Europe PubMed Central

PubMed publication ID

2848206

retrieved

25 May 2018

reference URL

http://europepmc.org/abstract/MED/2848206

PubMed publication ID

2848206

1 reference

stated in

Europe PubMed Central

PubMed publication ID

2848206

retrieved

25 May 2018

reference URL

http://europepmc.org/abstract/MED/2848206

 

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