Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone (Q43862866)

27 November 2017

title

Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone (English)

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27 November 2017

Michael S DeMott

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27 November 2017

Ergin Beyret

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27 November 2017

Donny Wong

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27 November 2017

Brian C Bales

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27 November 2017

Jae-Taeg Hwang

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27 November 2017

Marc M Greenberg

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27 November 2017

Bruce Demple

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27 November 2017

language of work or name

English

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publication date

22 January 2002

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

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27 November 2017

page(s)

7637-7640

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Regulation of eukaryotic abasic endonucleases and their role in genetic stability

27 November 2017

cites work

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The base excision repair pathway

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Removal by human apurinic/apyrimidinic endonuclease 1 (Ape 1) and Escherichia coli exonuclease III of 3'-phosphoglycolates from DNA treated with neocarzinostatin, calicheamicin, and gamma-radiation.

21 January 2018

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The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III.

21 January 2018

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Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

21 January 2018

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Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry

21 January 2018

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The reactivity of the 2-deoxyribonolactone lesion in single-stranded DNA and its implication in reaction mechanisms of DNA damage and repair

21 January 2018

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

21 January 2018

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

21 January 2018

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Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair

21 January 2018

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Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

21 January 2018

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

21 January 2018

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Effect of flap modifications on human FEN1 cleavage

21 January 2018

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Catalytic Center of DNA Polymerase β for Excision of Deoxyribose Phosphate Groups†

21 January 2018

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Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activity

21 January 2018

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The type of DNA glycosylase determines the base excision repair pathway in mammalian cells

21 January 2018

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Excision of C-4'-oxidized deoxyribose lesions from double-stranded DNA by human apurinic/apyrimidinic endonuclease (Ape1 protein) and DNA polymerase beta

21 January 2018

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Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C100577200

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27 November 2017

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