Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin (Q43789225)

26 November 2017

title

Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin (English)

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26 November 2017

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Yang M

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26 November 2017

Hogan SP

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26 November 2017

Henry PJ

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26 November 2017

Matthaei KI

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26 November 2017

McKenzie AN

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26 November 2017

Young IG

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26 November 2017

Rothenberg ME

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26 November 2017

Foster PS

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26 November 2017

publication date

1 October 2001

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American Journal of Respiratory Cell and Molecular Biology

26 November 2017

published in

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26 November 2017

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26 November 2017

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26 November 2017

page(s)

522-530

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Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity

26 November 2017

cites work

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Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.

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Interleukin-13: central mediator of allergic asthma

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Requirement for IL-13 independently of IL-4 in experimental asthma

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IL-12/IL-13 axis in allergic asthma

21 January 2018

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

21 January 2018

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21 January 2018

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The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor

21 January 2018

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IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain

21 January 2018

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Essential role of Stat6 in IL-4 signalling

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Regulation of T helper type 2 cell immunity by interleukin-4 and interleukin-13.

21 January 2018

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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

21 January 2018

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Localization of human interleukin 13 receptor in non-haematopoietic cells

21 January 2018

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Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity

21 January 2018

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Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice

21 January 2018

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Fundamental signals that regulate eosinophil homing to the gastrointestinal tract

21 January 2018

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Chemokine production by the BEAS-2B human bronchial epithelial cells: differential regulation of eotaxin, IL-8, and RANTES by TH2- and TH1-derived cytokines

21 January 2018

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Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1165/AJRCMB.25.4.4620

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26 November 2017

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