Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. (Q43691949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479297%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5 (English)

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9 November 2019

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9 November 2019

Jacob AL

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9 November 2019

Lund J

series ordinal

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9 November 2019

Hedin L

series ordinal

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9 November 2019

language of work or name

English

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publication date

30 July 2001

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

276

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9 November 2019

issue

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9 November 2019

page(s)

37659-37664

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A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development

9 November 2019

cites work

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Steroidogenic factor 1: a key determinant of endocrine development and function

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Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene

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Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1.

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Regulation of expression of the steroidogenic acute regulatory protein (StAR) gene: a central role for steroidogenic factor 1.

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

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The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus

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A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

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Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress

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Multiple steroidogenic factor 1 binding elements in the human steroidogenic acute regulatory protein gene 5'-flanking region are required for maximal promoter activity and cyclic AMP responsiveness.

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The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3',5'-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase).

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Regulation of the rat aromatase gene in ovarian granulosa cells and R2C Leydig cells

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Synergistic activation of the inhibin alpha-promoter by steroidogenic factor-1 and cyclic adenosine 3',5'-monophosphate

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Mutations in the activation function-2 core domain of steroidogenic factor-1 dominantly suppresses PKA-dependent transactivation of the bovine CYP17 gene

21 January 2018

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Steroidogenic factor-1 contains a carboxy-terminal transcriptional activation domain that interacts with steroid receptor coactivator-1.

21 January 2018

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Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300.

21 January 2018

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Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

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Transcription factor-specific requirements for coactivators and their acetyltransferase functions

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Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

21 January 2018

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Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

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Regulation of activity of the transcription factor GATA-1 by acetylation

21 January 2018

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

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Regulation of E2F1 activity by acetylation

21 January 2018

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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation

21 January 2018

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Mutually exclusive interactions of two nuclear orphan receptors determine activity of a cyclic adenosine 3',5'-monophosphate-responsive sequence in the bovine CYP17 gene

21 January 2018

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Acetylation of importin-alpha nuclear import factors by CBP/p300.

21 January 2018

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Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide

21 January 2018

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Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

21 January 2018

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Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation

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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA

21 January 2018

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The CBP co-activator is a histone acetyltransferase

21 January 2018

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Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation

21 January 2018

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Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo.

21 January 2018

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Increased affinity of c-Myb for CREB-binding protein (CBP) after CBP-induced acetylation

21 January 2018

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Acetylation regulates transcription factor activity at multiple levels

21 January 2018

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Histone acetylation in chromatin structure and transcription

21 January 2018

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Three proteins define a class of human histone deacetylases related to yeast Hda1p

21 January 2018

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Deacetylation of p53 modulates its effect on cell growth and apoptosis

21 January 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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21 January 2018

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21 January 2018

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21 January 2018

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The Gcn5.Ada complex potentiates the histone acetyltransferase activity of Gcn5

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M104427200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479297%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

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