Targeting expression of a transgene to the airway surface epithelium using a ciliated cell-specific promoter (Q43671300)

25 November 2017

title

Targeting expression of a transgene to the airway surface epithelium using a ciliated cell-specific promoter (English)

1 reference

25 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

transgene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

genetic vector

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

promoter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00221-1

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00221-1

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00221-1

18 March 2024

Kelly Zakel

1 reference

25 November 2017

Lawrence E. Ostrowski

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

James R. Hutchins

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

Wanda K. O'Neal

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

18 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14529837

18 March 2024

publication date

1 October 2003

1 reference

full work available at URL

25 November 2017

http://www.cell.com/article/S1525001603002211/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14529837

https://api.elsevier.com/content/article/PII:S1525001603002211?httpAccept=text/xml

18 March 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S1525-0016(03)00221-1

https://api.elsevier.com/content/article/PII:S1525001603002211?httpAccept=text/plain

18 March 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S1525-0016(03)00221-1

18 March 2024

1 reference

25 November 2017

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25 November 2017

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25 November 2017

page(s)

637-645

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https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

25 November 2017

1 reference

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An overview of the pathogenesis of cystic fibrosis lung disease

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Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

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Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

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Status of gene therapy for cystic fibrosis lung disease

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Gene therapy for cystic fibrosis: challenges and future directions

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Enhanced in vivo airway gene transfer via transient modification of host barrier properties with a surface-active agent

1 reference

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Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

1 reference

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Enhanced epithelial gene transfer by modulation of tight junctions with sodium caprate.

1 reference

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Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

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Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells

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Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors

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Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain

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Outcry greets US plan to test smallpox vaccine on children

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Progenitor-progeny relationships in airway epithelium

1 reference

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The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo

1 reference

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7 January 2021

Forkhead transcription factor HFH-4 expression is temporally related to ciliogenesis

1 reference

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Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium

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The human hepatocyte nuclear factor 3/fork head gene FKHL13: genomic structure and pattern of expression

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Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration

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A generic intron increases gene expression in transgenic mice

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Beta IV is the major beta-tubulin isotype in bovine cilia.

1 reference

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7 January 2021

Beta-globin YAC transgenes exhibit uniform expression levels but position effect variegation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Submucosal glands are the predominant site of CFTR expression in the human bronchus

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

In vivo analysis of DNase I hypersensitive sites in the human CFTR gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

CFTR intron 1 increases luciferase expression driven by CFTR 5'-flanking DNA in a yeast artificial chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Regulatable promoters for use in gene therapy applications: modification of the 5'-flanking region of the CFTR gene with multiple cAMP response elements to support basal, low-level gene expression that can be upregulated by exogenous agents that rai

1 reference

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7 January 2021

Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl- secretion

1 reference

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7 January 2021

Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR

1 reference

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7 January 2021

Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

Targeting transgene expression to airway epithelia and submucosal glands, prominent sites of human CFTR expression

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900221-1

7 January 2021

A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

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7 January 2021

Targeting transgene expression for cystic fibrosis gene therapy

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Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

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Identification of seven rat axonemal dynein heavy chain genes: expression during ciliated cell differentiation

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18 March 2024

Identifiers

DOI

1 reference

25 November 2017

1 reference