Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. (Q43072360)

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2 January 2020

title

Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling (English)

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2 January 2020

1 reference

Protein tyrosine phosphatase, receptor type, C

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Protein tyrosine phosphatase, receptor type, J

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Jing W Zhu

series ordinal

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2 January 2020

Tamiko R Katsumoto

series ordinal

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2 January 2020

Joseph Lin

series ordinal

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2 January 2020

language of work or name

English

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publication date

31 January 2008

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2 January 2020

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2 January 2020

volume

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issue

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2 January 2020

page(s)

183-196

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DEP-1 protein tyrosine phosphatase inhibits proliferation and migration of colon carcinoma cells and is upregulated by protective nutrients

2 January 2020

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25 May 2018

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Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation

25 May 2018

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CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

25 May 2018

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A deletion in the gene encoding the CD45 antigen in a patient with SCID.

25 May 2018

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Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

25 May 2018

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25 May 2018

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25 May 2018

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The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells

25 May 2018

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25 May 2018

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Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Impairment of T and B Cell Development by Treatment with a Type I Interferon

25 May 2018

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A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

25 May 2018

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Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines

25 May 2018

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CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion

25 May 2018

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25 May 2018

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CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

25 May 2018

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25 May 2018

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25 May 2018

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Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

25 May 2018

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25 May 2018

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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

25 May 2018

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Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas

25 May 2018

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Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)

25 May 2018

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Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

25 May 2018

1 reference

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Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.

25 May 2018

1 reference

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CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265106

The juxtamembrane wedge negatively regulates CD45 function in B cells.

15 August 2018

1 reference

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Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265106

Regulated expression of the receptor-like tyrosine phosphatase CD148 on hemopoietic cells

15 August 2018

1 reference

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LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21.

15 August 2018

1 reference

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Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease

15 August 2018

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12 December 2020

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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12 December 2020

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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12 December 2020

CD45 modulates phosphorylation of both autophosphorylation and negative regulatory tyrosines of Lyn in B cells

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12 December 2020

10.1016/J.IMMUNI.2007.11.024

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18249142%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18249142%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

18249142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18249142%20AND%20SRC:MED&resulttype=core&format=json