Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease (Q43059453)

From Wikidata

Jump to navigation Jump to search

scientific article published in May 2010

edit

Language	Label	Description	Also known as
English	Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease	scientific article published in May 2010

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20484629

retrieved

13 November 2017

title

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20484629

retrieved

13 November 2017

main subject

Alzheimer's disease

0 references

cell death

1 reference

based on heuristic

inferred from title

author

Jun Wan

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Zhenguo Wu

series ordinal

9

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

A K Fu

series ordinal

2

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

author name string

Fanny C F Ip

series ordinal

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Ho-Keung Ng

series ordinal

4

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Guylène Page

series ordinal

6

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Jerry H Wang

series ordinal

7

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Kwok-On Lai

series ordinal

8

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Nancy Y Ip

series ordinal

10

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

Jacques Hugon

series ordinal

5

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

language of work or name

English

0 references

publication date

1 May 2010

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20484629

retrieved

13 November 2017

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

volume

30

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

issue

20

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

page(s)

6873-6881

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

describes a project that uses

ImageJ

1 reference

stated in

Europe PubMed Central

retrieved

11 June 2022

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632652/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gp-41-mediated astrocyte inducible nitric oxide synthase mRNA expression: involvement of interleukin-1beta production by microglia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthases: targets for therapeutic strategies in neurological diseases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing and cell biological functions of the amyloid precursor protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of STAT3 defined by tissue-specific gene targeting

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stats: transcriptional control and biological impact

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topographic regulation of kinase activity in Alzheimer's disease brains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt/GSK3beta serine/threonine kinases: evidence for a signalling pathway mediated by familial Alzheimer's disease mutations

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glia and their cytokines in progression of neurodegeneration

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating biomarkers of cognitive decline and dementia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential role of Jak-STAT signaling in retinal degenerations

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plaques, tangles, and memory loss in mouse models of neurodegeneration.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease models and human neuropathology: similarities and differences

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GSK3 hypothesis of Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide toxicity in differentiated PC12 cells: calpain-calpastatin, caspase, and membrane damage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of neuroimmunomodulation in Alzheimer's disease.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid beta protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregated Amyloid-β Protein Induces Cortical Neuronal Apoptosis and Concomitant “Apoptotic” Pattern of Gene Induction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20484629

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.0519-10.2010

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

PMC publication ID

6632652

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

PubMed publication ID

20484629

1 reference

stated in

Europe PubMed Central

PMC publication ID

6632652

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632652&resulttype=core&format=json

retrieved

15 May 2020

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43059453&oldid=1979141207"