Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors (Q43026301)

From Wikidata

Jump to navigation Jump to search

scientific article published in August 2010

Synthesis, 3D-QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

Language	Label	Description	Also known as
English	Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors	scientific article published in August 2010	Synthesis, 3D-QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Eduardo Domínguez

object named as

Eduardo Domínguez

5

0 references

Christian F Masaguer

object named as

Christian F Masaguer

4

0 references

object named as

Jana Selent

2

0 references

object named as

José Brea

7

0 references

object named as

Manuel Pastor

10

0 references

author name string

Laura López

1

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Raquel Ortega

3

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Filipe Areias

6

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

María Isabel Loza

8

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2010

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

1300-1317

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

21 January 2018

Dopamine receptors: molecular biology, biochemistry and behavioural aspects

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine receptors: from structure to function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Possible implications of the dopamine D(3) receptor in schizophrenia and in antipsychotic drug actions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine D3 receptor antagonists as therapeutic agents

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined alpha2 and D2/3 receptor blockade enhances cortical glutamatergic transmission and reverses cognitive impairment in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: III. Actions in models of therapeutic

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of novel 1,2,3,4-tetrahydroisoquinoline derivatives and closely related compounds as potent and selective dopamine D3 receptor ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Multi-receptor binding profile of clozapine and olanzapine: a structural study based on the new beta2 adrenergic receptor template

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and validation of AMANDA, a new algorithm for selecting highly relevant regions in Molecular Interaction Fields.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

A single amino acid difference accounts for the pharmacological distinctions between the rat and human 5-hydroxytryptamine1B receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of dopamine D3 receptor binding site by pharmacological characterization of mutants expressed in CHO cells with the Semliki Forest virus system

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and pharmacological screening of some N-(4-substituted-piperazin-1-ylalkyl)-3,4-pyrroledicarboximides

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Preparation of novel derivatives of pyridothiazine-1,1-dioxide and their CNS and antioxidant properties.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and structure-activity relationships of new arylpiperazines: para substitution with electron-withdrawing groups decrease binding to 5-HT(1A) and D(2A) receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-activity relationship studies of CNS agents, XV: N-[omega-(4-aryl-1-piperazinyl)alkyl]-2-oxo-1,2,3,4-tetrahydroquinoline s and -4-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indoles: new, highly potent 5-HT1A ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and SAR of highly potent and selective dopamine D(3)-receptor antagonists: Quinolin(di)one and benzazepin(di)one derivatives. herve.geneste@abbott.com

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Conformational changes of G protein-coupled receptors during their activation by agonist binding

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand induced conformational states of the 5-HT(1A) receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Automatic generation of 3D-atomic coordinates for organic molecules

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved protein-ligand docking using GOLD

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Site-directed mutagenesis of the human dopamine D2 receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Generating Optimal Linear PLS Estimations (GOLPE): An Advanced Chemometric Tool for Handling 3D-QSAR Problems

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000101

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CMDC.201000101

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43026301&oldid=2245999494"