Co-engagement of alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells. (Q42951539)

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scientific article published on January 2010

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English	Co-engagement of alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells.	scientific article published on January 2010

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9 February 2020

Co-engagement of alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells (English)

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9 February 2020

Krishna V Komanduri

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9 February 2020

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Tae Kon Kim

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9 February 2020

Matthew J Billard

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9 February 2020

Eric D Wieder

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9 February 2020

Bradley W McIntyre

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9 February 2020

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1 January 2010

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9 February 2020

Human Immunology

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9 February 2020

71

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9 February 2020

1

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9 February 2020

23-28

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Vaccines with enhanced costimulation maintain high avidity memory CTL.

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1 reference

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CD28 ligation in T-cell activation: evidence for two signal transduction pathways

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The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

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CD4 and CD8 regulate interleukin 2 responses of T cells

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Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

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CD45RA T-cell activation without proliferation by a partial agonist monoclonal antibody to beta1 integrin

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1 reference

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Accessory cell-T cell interactions involved in anti-CD3-induced T4 and T8 cell proliferation: analysis with monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19815047

12 December 2020

based on heuristic

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Regulation of T cell proliferation by anti-CD49d and anti-CD29 monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19815047

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Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increas

1 reference

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A VLA-4 alpha-chain specific monoclonal antibody enhances CD3-induced IL-2/IL-2 receptor-dependent T-cell proliferation

1 reference

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Alpha 4 beta 1 (CD49d/CD29) integrin costimulation of human T cells enhances transcription factor and cytokine induction in the absence of altered sensitivity to anti-CD3 stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19815047

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inferred from PubMed ID database lookup

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

1 reference

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10.1016/J.HUMIMM.2009.09.360

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9 February 2020

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9 February 2020

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9 February 2020

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