BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats (Q42912136)

11 November 2017

title

BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats (English)

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11 November 2017

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ChEBI release 2020-05-28

ChEBI ID

142435

pulmonary hypertension

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based on heuristic

inferred from title

author

Johannes-Peter Stasch

object named as

Johannes-Peter Stasch

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11 November 2017

Lise Bech Thorsen

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11 November 2017

Yvonne Eskildsen-Helmond

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11 November 2017

Helle Zibrandtsen

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11 November 2017

Ulf Simonsen

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11 November 2017

Britt Elmedal Laursen

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11 November 2017

language of work or name

English

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publication date

7 September 2010

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full work available at URL

11 November 2017

https://api.elsevier.com/content/article/PII:S0014299910008368?httpAccept=text/xml

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Crossref

DOI

https://api.crossref.org/works/10.1016/J.EJPHAR.2010.08.032

https://api.elsevier.com/content/article/PII:S0014299910008368?httpAccept=text/plain

9 July 2024

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Crossref

DOI

https://api.crossref.org/works/10.1016/J.EJPHAR.2010.08.032

European Journal of Pharmacology

9 July 2024

published in

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11 November 2017

volume

647

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11 November 2017

issue

1-3

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11 November 2017

page(s)

147-154

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Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats

11 November 2017

cites work

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BAY 41-2272 [5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]pyrimidin-4-ylamine]-induced dilation in ovine pulmonary artery: role of sodium pump

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Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism.

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BAY 41-2272, a Direct Activator of Soluble Guanylate Cyclase, Reduces Right Ventricular Hypertrophy and Prevents Pulmonary Vascular Remodeling during Chronic Hypoxia in Neonatal Rats

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Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

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The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats.

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Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor

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Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs

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Hypoxia decreases expression of soluble guanylate cyclase in cultured rat pulmonary artery smooth muscle cells

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Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS.

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Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide

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Soluble guanylyl cyclase during postnatal porcine pulmonary maturation.

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Diminished NO release in chronic hypoxic human endothelial cells

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The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts

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Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.

9 July 2024

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Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

9 July 2024

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Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

9 July 2024

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Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension

9 July 2024

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NO-independent regulatory site on soluble guanylate cyclase

9 July 2024

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9 July 2024

Identifiers

DOI

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11 November 2017

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