CD28/CD154 blockade prevents autoimmune diabetes by inducing nondeletional tolerance after effector t-cell inhibition and regulatory T-cell expansion (Q42918712)

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scientific article published on 20 May 2008

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English	CD28/CD154 blockade prevents autoimmune diabetes by inducing nondeletional tolerance after effector t-cell inhibition and regulatory T-cell expansion	scientific article published on 20 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

CD28/CD154 blockade prevents autoimmune diabetes by inducing nondeletional tolerance after effector t-cell inhibition and regulatory T-cell expansion (English)

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

author name string

Mark R Rigby

1

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Alison M Trexler

2

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Thomas C Pearson

3

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Christian P Larsen

4

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

language of work or name

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publication date

20 May 2008

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Europe PubMed Central

PMC publication ID

11 November 2017

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Europe PubMed Central

PMC publication ID

11 November 2017

57

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Europe PubMed Central

PMC publication ID

11 November 2017

10

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

2672-2683

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Cellular and molecular pathogenesis of type 1A diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

FOXP3 modifies the phenotypic and functional properties of regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation

1 reference

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27 May 2018

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

1 reference

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27 May 2018

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

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27 May 2018

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

1 reference

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27 May 2018

How do CD4+CD25+ regulatory T cells control autoimmunity?

1 reference

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27 May 2018

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

T cell homeostasis in tolerance and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

1 reference

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27 May 2018

The NOD mouse: a model of immune dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

The new paradigm of T-cell homeostatic proliferation-induced autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

The pathogenesis of diabetes in the NOD mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Homeostatic proliferation is a barrier to transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Cytokines and autoimmunity: redundancy defines their complex nature

1 reference

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27 May 2018

Immunotherapy as a means to induce transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Induction of immunologic tolerance for transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

The BB/Wor rat and the balance hypothesis of autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

27 May 2018

CLinical experience acquired with the efalizumab (Raptiva) (CLEAR) trial in patients with moderate-to-severe plaque psoriasis: results from a phase III international randomized, placebo-controlled trial.

1 reference

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16 August 2018

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

16 August 2018

Prolonged islet allograft survival in diabetic NOD mice by targeting CD45RB and CD154.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

16 August 2018

Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

16 August 2018

Following the development of a CD4 T cell response in vivo: from activation to memory formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

16 August 2018

CD28-B7 T cell costimulatory blockade by CTLA4Ig in the rat renal allograft model: inhibition of cell-mediated and humoral immune responses in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

3 November 2018

CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

3 November 2018

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

3 November 2018

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551677

1 December 2018

Homeostatic expansion occurs independently of costimulatory signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of autoimmune diabetes by non-islet-specific T cells - a role for the glucocorticoid-induced TNF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic control of diabetes progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/18492787

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB07-1712

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

ResearchGate publication ID

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