Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond (Q42857321)

8 November 2017

Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond (English)

1 reference

8 November 2017

P B Armstrong

1 reference

8 November 2017

J P Quigley

series ordinal

1 reference

8 November 2017

language of work or name

English

0 references

publication date

1 December 1987

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8 November 2017

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8 November 2017

248

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8 November 2017

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8 November 2017

703-707

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The Action of Ammonia on Complement. The Fourth Component

8 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Autolytic fragmentation of complement components C3 and C4 under denaturing conditions, a property shared with α 2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

The covalent-binding reaction of complement component C3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Sequence determination of the thiolester site of the fourth component of human complement.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Covalent binding and hemolytic activity of complement proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Evidence for presence of an internal thiolester bond in third component of human complement.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Covalent thrombin-.alpha.2-macroglobulin complexes. Evidence for bivalent crosslinking of inhibitor chains by a single enzyme molecule

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Theβ-Cys-γ-Glu thiolester bond in human C3, C4, andα 2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Conformation and protease binding activity of binary and ternary human alpha 2-macroglobulin-protease complexes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Ligand binding, conformational change and plasma elimination of human, mouse and rat α-macroglobulin proteinase inhibitors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Residual α2-macroglobulin in fetal calf serum and properties of its complex with thrombin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Evolution of α2-macroglobulin. The purification and characterization of a protein homologous with human α2-macroglobulin from plaice (Pleuronectes platessa L.) plasma

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Further characterization of the covalent linking reaction of α2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Inhibition of alpha 2-macroglobulin-bound trypsin by soybean trypsin inhibitor.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Amino acid sequence of the tryptic peptide containing the alkylamine-reactive site from human alpha 2-macroglobulin. Identification of gamma-glutamylmethylamide

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Methylamine reaction and denaturation-dependent fragmentation of complement component 3. Comparison with alpha2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Complement and complement-like activity in lower vertebrates and invertebrates

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Proteinase inhibitory activity released from the horseshoe crab blood cell during exocytosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Rat plasma alpha 1-inhibitor3: a member of the alpha-macroglobulin family.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Kinetics of the reaction of thrombin and alpha 2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Changes of the proteinase binding properties and conformation of bovine alpha 2-macroglobulin on cleavage of the thio ester bonds by methylamine

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Characterization of alkylamine-sensitive site in alpha 2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Heat-induced fragmentation of human alpha 2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Structural characterization of human alpha2-macroglobulin subunits

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Physical and chemical properties of human plasma β2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Human alpha2-macroglobulin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Evidence for an ester linkage between the labile binding site of C3b and receptive surfaces

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Fourth component of human complement: studies of an amine-sensitive site comprised of a thiol component.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

The binding of human complement component C4 to antibody-antigen aggregates

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Kinetics of the conformational alterations associated with nucleophilic modification of .alpha.2-macrobglobulin

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Covalent binding of proteinases in their reaction with α2-macroglobulin

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

An endopeptidase inhibitor, similar to mammalian alpha 2-macroglobulin, detected in the hemolymph of an invertebrate, Limulus polyphemus

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

An α2-macroglobulinlike activity in the blood of chelicerate and mandibulate arthropods

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1148606

Subunit Structure of the Rat α-Macroglobulin Proteinase Inhibitors

1 December 2018

1 reference

12 December 2020

Alpha 2-macroglobulin-protease reactions: relationship of covalent bond formation, methylamine reactivity, and specific proteolysis

1 reference

12 December 2020

Functional modifications of alpha 2-macroglobulin by primary amines. II. Inhibition of covalent binding of trypsin to alpha 2 M by methylamine and other primary amines

1 reference

12 December 2020

Mechanism of proteinase complex formation with alpha 2-macroglobulin. Three modes of trypsin binding

1 reference

12 December 2020

Determination of alpha-2-macroglobulin as trypsin-protein esterase

1 reference

12 December 2020

Third component of human complement: structural requirements for its function

1 reference

12 December 2020

Ovostatin: a novel proteinase inhibitor from chicken egg white. I. Purification, physicochemical properties, and tissue distribution of ovostatin

1 reference

12 December 2020

Comparison of the binding of chicken α-macroglobulin and ovomacroglobulin to the mammalian α2-macroglobulin receptor

1 reference

12 December 2020

Characterization of an Amine-Reactive, Heat-Labile Acyl Residue in the Fourth Component of Human Complement, C41

1 reference

12 December 2020

Identification of “embryonin” as bovine alpha 2-macroglobulin

1 reference

12 December 2020

Interaction of α2-macroglobulin with trypsin, chymotrypsin, plasmin, and papain

1 reference

12 December 2020

Isolation and description of proteins related to the human complement system

1 reference

12 December 2020

Third component of human complement: appearance of a sulfhydryl group following chemical or enzymatic inactivation

1 reference

12 December 2020

Trypsin-induced activation of the thiol esters in α2-macroglobulin generates a short-lived intermediate (‘nascent’ α2M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity

1 reference

12 December 2020

Characterization of thrombin binding to alpha 2-macroglobulin

1 reference

12 December 2020

Alpha 2-macroglobulin: an introduction

1 reference

12 December 2020

The preparation and properties of two new chromogenic substrates of trypsin

1 reference

12 December 2020

A thiol-ester in α2-macroglobulin cleaved during proteinase complex formation

1 reference

12 December 2020

Localization of the two protease binding sites in human alpha 2-macroglobulin

1 reference

12 December 2020

Human alpha-2-macroglobulin. Studies on the electrophoretic heterogeneity

1 reference

12 December 2020

Effect of methylamine on the structure and function of the fourth component of human complement, C4

1 reference

12 December 2020

Endotoxin-induced degranulation of the Limulus amebocyte

1 reference

12 December 2020

The reaction of alpha 2-macroglobulin-bound trypsin with soybean trypsin inhibitor

1 reference

12 December 2020

Generation and reactivity of "nascent" alpha 2-macroglobulin: localization of cross-links in alpha 2-macroglobulin-trypsin complex

1 reference

12 December 2020

Limited Proteolysis of the Third Component of Human Complement, C3, by Heat Treatment

1 reference

12 December 2020

Molecular alteration of alpha-2-macroglobulin by aliphatic amines

1 reference

12 December 2020

Kinetics of appearance of sulfhydryl groups in .alpha.2-macroglobulin on reaction of the inhibitor with amines

1 reference

12 December 2020

Nuclear magnetic resonance study of interaction of ligands with streptococcus faecium dihydrofolate reductase labeled with [gamma-13C]tryptophan

1 reference

12 December 2020

Treatment of human complement components C4 and C3 with amines or chaotropic ions. Evidence of a functional and structural change that provides uncleaved C4 and C3 with properties of their soluble activated froms, C4b and C3b

1 reference

12 December 2020

A homologue of alpha 2-macroglobulin purified from the hemolymph of the horseshoe crab Limulus polyphemus

1 reference

12 December 2020

Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity

1 reference

12 December 2020

Inhibition of proteases by alpha 2-macroglobulin. The role of lysyl amino groups of trypsin in covalent complex formation

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2480703

1 reference

8 November 2017

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8 November 2017

PubMed publication ID

2449170

1 reference