Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant (Q42834452)

8 November 2017

title

Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant (English)

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8 November 2017

Balazs Debreceni

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8 November 2017

Yuan Gao

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8 November 2017

Fukun Guo

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8 November 2017

Kejin Zhu

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8 November 2017

Baoqing Jia

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8 November 2017

Yi Zheng

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8 November 2017

language of work or name

English

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publication date

3 November 2003

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Journal of Biological Chemistry

8 November 2017

published in

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8 November 2017

volume

279

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8 November 2017

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8 November 2017

page(s)

3777-3786

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Rho GTPases and signaling networks

8 November 2017

cites work

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

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Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

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21 January 2018

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NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

21 January 2018

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Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

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21 January 2018

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The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 January 2018

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21 January 2018

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A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.

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21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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21 January 2018

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RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity

21 January 2018

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UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

21 January 2018

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Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

21 January 2018

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The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M308282200

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8 November 2017

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