Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells. (Q42822924)

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5 January 2020

title

Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells (English)

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5 January 2020

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5 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15576379%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Maria Simon

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15576379%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Lesley Vanes

series ordinal

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5 January 2020

language of work or name

English

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publication date

2 December 2004

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Journal of Biological Chemistry

5 January 2020

published in

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volume

280

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issue

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page(s)

4510-4517

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Mast cell signal transduction from the high-affinity IgE receptor

5 January 2020

cites work

1 reference

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Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE.

21 January 2018

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Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides

21 January 2018

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Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410326200

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

21 January 2018

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Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.

21 January 2018

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Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

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Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

21 January 2018

1 reference

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Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells

21 January 2018

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

21 January 2018

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Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase

21 January 2018

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Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

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Depolarization of rat basophilic leukemia cells inhibits calcium uptake and exocytosis

21 January 2018

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Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line

21 January 2018

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Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation

21 January 2018

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Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells.

21 January 2018

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The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction

21 January 2018

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

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Rac and phosphatidylinositol 3-kinase regulate the protein kinase B in Fc epsilon RI signaling in RBL 2H3 mast cells

21 January 2018

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Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

21 January 2018

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Molecular adapters in Fc(epsilon)RI signaling and the allergic response

21 January 2018

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Phospholipase C gamma 2 is essential for specific functions of Fc epsilon R and Fc gamma R

21 January 2018

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Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

21 January 2018

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Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase

21 January 2018

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