Ubiquitin chain trimming recycles the substrate binding sites of the 26 S proteasome and promotes degradation of lysine 48-linked polyubiquitin conjugates (Q42821759)

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scientific article published on June 2011

Language	Label	Description	Also known as
English	Ubiquitin chain trimming recycles the substrate binding sites of the 26 S proteasome and promotes degradation of lysine 48-linked polyubiquitin conjugates	scientific article published on June 2011

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Ubiquitin chain trimming recycles the substrate binding sites of the 26 S proteasome and promotes degradation of lysine 48-linked polyubiquitin conjugates (English)

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

ubiquitin-proteasome system

0 references

author name string

Nan-Yan Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Andrew D Jacobson

2

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Andrea Macfadden

3

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Chang-Wei Liu

4

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

language of work or name

0 references

publication date

1 June 2011

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Europe PubMed Central

PMC publication ID

8 November 2017

number of pages

7

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

286

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

29

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

25540-25546

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Degradation of some polyubiquitinated proteins requires an intrinsic proteasomal binding element in the substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

The role of ubiquitin in NF-kappaB regulatory pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Recognition and processing of ubiquitin-protein conjugates by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Nonproteolytic functions of ubiquitin in cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Proteasome subunit Rpn13 is a novel ubiquitin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Multiple associated proteins regulate proteasome structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

A cryptic protease couples deubiquitination and degradation by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Recognition of the polyubiquitin proteolytic signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

27 May 2018

Ubiquitin chain synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

16 August 2018

Purification and characterization of UBP6, a new ubiquitin-specific protease in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138263

16 August 2018

Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome.

1 reference

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16 August 2018

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.260505

21 January 2018

Nonhydrolyzable diubiquitin analogues are inhibitors of ubiquitin conjugation and deconjugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632534

12 December 2020

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Identifiers

10.1074/JBC.M111.260505

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

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