Gene trapping identifies inhibitors of oncogenic transformation. The tissue inhibitor of metalloproteinases-3 (TIMP3) and collagen type I alpha2 (COL1A2) are epidermal growth factor-regulated growth repressors (Q42829691)

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scientific article published on May 1998

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English	Gene trapping identifies inhibitors of oncogenic transformation. The tissue inhibitor of metalloproteinases-3 (TIMP3) and collagen type I alpha2 (COL1A2) are epidermal growth factor-regulated growth repressors	scientific article published on May 1998

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 November 2017

Gene trapping identifies inhibitors of oncogenic transformation. The tissue inhibitor of metalloproteinases-3 (TIMP3) and collagen type I alpha2 (COL1A2) are epidermal growth factor-regulated growth repressors (English)

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Europe PubMed Central

PubMed publication ID

8 November 2017

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inferred from title

Harald von Melchner

5

object named as

von Melchner H

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Europe PubMed Central

PubMed publication ID

8 November 2017

author name string

Andreú T

1

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Europe PubMed Central

PubMed publication ID

8 November 2017

Beckers T

2

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Europe PubMed Central

PubMed publication ID

8 November 2017

Thoenes E

3

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Europe PubMed Central

PubMed publication ID

8 November 2017

Hilgard P

4

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Europe PubMed Central

PubMed publication ID

8 November 2017

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publication date

1 May 1998

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8 November 2017

number of pages

7

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Journal of Biological Chemistry

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Europe PubMed Central

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8 November 2017

273

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Europe PubMed Central

PubMed publication ID

8 November 2017

22

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Europe PubMed Central

PubMed publication ID

8 November 2017

13848-13854

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Europe PubMed Central

PubMed publication ID

8 November 2017

Selective disruption of genes expressed in totipotent embryonal stem cells

1 reference

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A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice

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Analysis of lipopolysaccharide-response genes in B-lineage cells demonstrates that they can have differentiation stage-restricted expression and contain SH2 domains.

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Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.

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Analysis of mammalian cell genetic regulation in situ by using retrovirus-derived "portable exons" carrying the Escherichia coli lacZ gene

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A murine homolog of the yeast RNA1 gene is required for postimplantation development.

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Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice

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Fluorescence-activated sorting of totipotent embryonic stem cells expressing developmentally regulated lacZ fusion genes

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Identification of genes induced by factor deprivation in hematopoietic cells undergoing apoptosis using gene-trap mutagenesis and site-specific recombination

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Signal transduction by receptors with tyrosine kinase activity

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Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

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Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts

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Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation

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Construction of a Full-Length Murine Proα2(I) Collagen cDNA by the Polymerase Chain Reaction

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Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure

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Dicistronic transcription units for gene expression in mammalian cells

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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An expression vector system for stable expression of oncogenes

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CD44 is the principal cell surface receptor for hyaluronate

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Isolation of cellular promoters by using a retrovirus promoter trap

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An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

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Functional genomics in mice by tagged sequence mutagenesis

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Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene

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A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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Transcriptional regulation by extracellular signals: mechanisms and specificity

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

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A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth

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Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3.

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Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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Enrichment of insertional mutants following retrovirus gene trap selection

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Matrix metalloproteinase inhibition: a review of anti-tumour activity

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Matrix metalloproteinases and the development of cancer

1 reference

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Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

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Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

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Matrix metalloproteinases: a review

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New insights into the function of collagens from genetic analysis

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Identifiers

10.1074/JBC.273.22.13848

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

ResearchGate publication ID

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