Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements (Q42828807)

8 November 2017

title

Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements (English)

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8 November 2017

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8 November 2017

Nielsen KH

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8 November 2017

Gredsted L

series ordinal

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8 November 2017

Willumsen BM

series ordinal

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8 November 2017

language of work or name

English

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publication date

1 April 2001

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8 November 2017

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inferred from page(s)

published in

Oncogene

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8 November 2017

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8 November 2017

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8 November 2017

page(s)

2091-2100

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Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf

8 November 2017

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

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Activation of R-Ras by Ras-guanine nucleotide-releasing factor

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All ras proteins are polyisoprenylated but only some are palmitoylated

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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R-Ras is regulated by activators and effectors distinct from those that control Ras function

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

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Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo

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Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1

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Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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Residues crucial for Ras interaction with GDP-GTP exchangers

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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

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Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

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RAS genes and growth control in Saccharomyces cerevisiae

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In yeast, RAS proteins are controlling elements of adenylate cyclase.

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Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

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New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

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The p21 ras C-terminus is required for transformation and membrane association

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Mutational analysis of a ras catalytic domain

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The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

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Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

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7 January 2021

Two distinct regions of Ras participate in functional interaction with GDP-GTP exchangers

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7 January 2021

Molecular cloning of two types of GAP complementary DNA from human placenta

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7 January 2021

Harvey murine sarcoma virus: influences of coding and noncoding sequences on cell transformation in vitro and oncogenicity in vivo.

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7 January 2021

22 Analysis of ras acylation sites: Mutagenesis and transfection

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204306

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Dimensions Publication ID

8 November 2017

1001031072

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