Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo (Q42809738)

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scientific article published on August 1996

Language	Label	Description	Also known as
English	Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo	scientific article published on August 1996

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

author name string

Domin J

1

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Europe PubMed Central

PubMed publication ID

7 November 2017

Dhand R

2

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

Waterfield MD

3

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

language of work or name

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publication date

1 August 1996

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Europe PubMed Central

PubMed publication ID

7 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

7 November 2017

271

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Europe PubMed Central

PubMed publication ID

7 November 2017

35

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Europe PubMed Central

PubMed publication ID

7 November 2017

21614-21621

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Europe PubMed Central

PubMed publication ID

7 November 2017

The biology of platelet-derived growth factor

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Signal transduction by the platelet-derived growth factor receptor

1 reference

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Signal transduction by receptors with tyrosine kinase activity

1 reference

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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Oncogenes and signal transduction

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

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The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp

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Early signals in the mitogenic response

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Platelet-derived growth factor elicits cyclic AMP accumulation in swiss 3T3 cells: Role of prostaglandin production

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

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Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1 reference

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A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

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Purification and characterization of bovine brain type I phosphatidylinositol kinase

1 reference

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Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 reference

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 reference

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21 January 2018

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 reference

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21 January 2018

The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85

1 reference

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21 January 2018

Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta

1 reference

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21 January 2018

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

1 reference

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21 January 2018

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

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21 January 2018

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system

1 reference

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21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

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21 January 2018

Association between the PDGF receptor and members of the src family of tyrosine kinases

1 reference

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21 January 2018

The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

1 reference

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21 January 2018

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking

1 reference

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21 January 2018

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor

1 reference

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21 January 2018

Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin

1 reference

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21 January 2018

Specific activity of phosphatidylinositol 3-kinase is increased by insulin stimulation

1 reference

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21 January 2018

Human colony stimulating factor-1 receptor activates the C-raf-1 proto-oncogene kinase

1 reference

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21 January 2018

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

1 reference

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21 January 2018

Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells

1 reference

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21 January 2018

Phosphorylation in vitro of the 85 kDa subunit of phosphatidylinositol 3-kinase and its possible activation by insulin receptor tyrosine kinase

1 reference

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21 January 2018

Characterization of the bovine brain cytosolic phosphatidylinositol 3-kinase complex

1 reference

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21 January 2018

Characterization of pp85, a target of oncogenes and growth factor receptors

1 reference

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21 January 2018

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

1 reference

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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The receptors for nerve growth factor and other neurotrophins

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IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

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Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit

1 reference

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21 January 2018

Identifiers

10.1074/JBC.271.35.21614

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 November 2017

ResearchGate publication ID

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