Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase (Q42807993)

7 November 2017

title

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase (English)

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7 November 2017

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Chen HC

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7 November 2017

Appeddu PA

series ordinal

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7 November 2017

Isoda H

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7 November 2017

Guan JL

series ordinal

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7 November 2017

language of work or name

English

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publication date

1 October 1996

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

271

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7 November 2017

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7 November 2017

page(s)

26329-26334

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Integrins: emerging paradigms of signal transduction

7 November 2017

cites work

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Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

21 January 2018

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

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Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

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Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

21 January 2018

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Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

21 January 2018

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Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain

21 January 2018

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Interaction of focal adhesion kinase with cytoskeletal protein talin

21 January 2018

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Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

21 January 2018

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

21 January 2018

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

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Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

21 January 2018

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Transformation of mammalian cells with genes from procaryotes and eucaryotes

21 January 2018

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Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

21 January 2018

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Oncogenes and signal transduction

21 January 2018

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Activation of phosphatidylinositol 3-kinase by insulin

21 January 2018

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Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation

21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

21 January 2018

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A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

21 January 2018

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

21 January 2018

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Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase

21 January 2018

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A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor

21 January 2018

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Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding

21 January 2018

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Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity

21 January 2018

1 reference

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The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.42.26329

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7 November 2017

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