In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo (Q42806057)

7 November 2017

title

In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo (English)

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7 November 2017

Takuya Nojima

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7 November 2017

Kei Haniuda

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7 November 2017

Tatsuya Moutai

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7 November 2017

Moeko Matsudaira

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7 November 2017

Sho Mizokawa

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7 November 2017

Ikuo Shiratori

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7 November 2017

Takachika Azuma

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7 November 2017

Daisuke Kitamura

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7 November 2017

language of work or name

English

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publication date

6 September 2011

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7 November 2017

published in

Nature Communications

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7 November 2017

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7 November 2017

page(s)

465

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

7 November 2017

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B-cell memory: are subsets necessary?

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Antigen-specific memory B cell development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Unique maturation program of the IgE response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Humoral immune responses in CD40 ligand-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

A critical role for IL-21 in regulating immunoglobulin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

A fundamental role for interleukin-21 in the generation of T follicular helper cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

New markers for murine memory B cells that define mutated and unmutated subsets

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Multiple layers of B cell memory with different effector functions

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Different B cell populations mediate early and late memory during an endogenous immune response

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Expression of IgD by murine lymphocytes. Loss of surface IgD indicates maturation of memory B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Novel role of the Ras cascade in memory B cell response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Generation of memory B cells and plasma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Mcl-1 is essential for germinal center formation and B cell memory

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS1475

Maintenance of B-cell memory by long-lived cells generated from proliferating precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Imaging of germinal center selection events during affinity maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Evolutionary and somatic selection of the antibody repertoire in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

DNA repair in antibody somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

B cell memory in xid mice is long-lived despite reduced memory B cell frequency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Two waves of memory B-cell generation in the primary immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Cell cycle arrest and apoptosis induced by Notch1 in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1475

Kinetics of establishing the memory B cell population as revealed by CD38 expression.

21 January 2018

1 reference

12 December 2020

Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-Ig down-regulates Fas expression of CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis

1 reference

12 December 2020

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner

1 reference

12 December 2020

The functional role of B cell antigen receptor stimulation and IL-4 in the generation of human memory B cells from germinal center B cells

1 reference

12 December 2020

A pivotal role for DNase I-sensitive regions 3b and/or 4 in the induction of somatic hypermutation of IgH genes

1 reference

12 December 2020

Evaluation of the conformational equilibrium of reduced hen egg lysozyme by antibodies to the native form

1 reference

12 December 2020

BCL-6 expression during B-cell activation

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12 December 2020

IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS1475

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Dimensions Publication ID

7 November 2017

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1006884759

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