Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages (Q42799246)

7 November 2017

title

Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages (English)

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7 November 2017

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7 November 2017

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7 November 2017

Yann Leverrier

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Antonio Bilancio

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Bart Vanhaesebroeck

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7 November 2017

Carol Sawyer

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7 November 2017

language of work or name

English

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publication date

16 July 2003

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

278

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7 November 2017

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7 November 2017

page(s)

38437-38442

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Phagocytosis and innate immunity

7 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M306649200

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

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Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

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Apoptotic cell removal

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Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

21 January 2018

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A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

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A requirement for phosphatidylinositol 3-kinase in pseudopod extension

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A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18)

21 January 2018

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21 January 2018

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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21 January 2018

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Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis

21 January 2018

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Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

21 January 2018

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Phosphatidylinositol 3-phosphate is generated in phagosomal membranes.

21 January 2018

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PI3-kinase inhibition: a target for drug development?

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In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways.

21 January 2018

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

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Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells

21 January 2018

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Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

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Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells

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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

21 January 2018

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N-terminal domains of the class ia phosphoinositide 3-kinase regulatory subunit play a role in cytoskeletal but not mitogenic signaling

21 January 2018

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21 January 2018

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A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells

21 January 2018

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Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

21 January 2018

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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

21 January 2018

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

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Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.

21 January 2018

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Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase

21 January 2018

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Membrane dynamics in phagocytosis

21 January 2018

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Rab5 regulates motility of early endosomes on microtubules

21 January 2018

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Association of phosphatidylinositol 3-kinase composed of p110beta-catalytic and p85-regulatory subunits with the small GTPase Rab5.

21 January 2018

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Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages

21 January 2018

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A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M306649200

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7 November 2017

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