The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain (Q42798095)

7 November 2017

title

The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain (English)

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7 November 2017

Drugan JK

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7 November 2017

Rogers-Graham K

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7 November 2017

Gilmer T

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7 November 2017

Campbell S

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7 November 2017

Clark GJ

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7 November 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

275

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7 November 2017

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7 November 2017

page(s)

35021-35027

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Pleckstrin homology domains: a common fold with diverse functions

7 November 2017

cites work

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The pleckstrin homology domain: an intriguing multifunctional protein module

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Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase

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Pleckstrin homology domains interact with filamentous actin

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Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo

21 January 2018

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Constitutive membrane association potentiates activation of Bruton tyrosine kinase

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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The PH domain: a common piece in the structural patchwork of signalling proteins

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Ras-GTPase activating protein (GAP): a putative effector for Ras

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Ras-GTPase activating protein inhibition specifically induces apoptosis of tumour cells

21 January 2018

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Identification of the SH3 Domain of GAP as an Essential Sequence for Ras-GAP-Mediated Signaling

21 January 2018

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Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain

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p120 GAP modulates Ras activation of Jun kinases and transformation

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Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein

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GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents

21 January 2018

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Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

21 January 2018

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Construction and applications of a highly transmissible murine retrovirus shuttle vector

21 January 2018

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Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

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Biological assays for Ras transformation

21 January 2018

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Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

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TC21 causes transformation by Raf-independent signaling pathways

21 January 2018

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The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

21 January 2018

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Raf-1 interferes with Ras and Rap1A effector functions in yeast

21 January 2018

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

21 January 2018

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Interactions between protein kinase C and pleckstrin homology domains. Inhibition by phosphatidylinositol 4,5-bisphosphate and phorbol 12-myristate 13-acetate

21 January 2018

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Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

21 January 2018

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Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.

21 January 2018

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

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Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits

21 January 2018

1 reference

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Refolding and purification of Ras proteins

21 January 2018

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Microtubule elongation and guanosine 5'-triphosphate hydrolysis. Role of guanine nucleotides in microtubule dynamics

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M004386200

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7 November 2017

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