Radiation and immunotherapy: a synergistic combination. (Q42724344)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863633%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Radiation and immunotherapy: a synergistic combination (English)

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5 March 2020

1 reference

Naomi Haas

1 reference

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5 March 2020

Neha Vapiwala

series ordinal

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5 March 2020

language of work or name

English

0 references

publication date

1 July 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863633%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

5 March 2020

published in

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5 March 2020

volume

123

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5 March 2020

issue

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5 March 2020

page(s)

2756-2763

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

5 March 2020

cites work

1 reference

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Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

27 May 2018

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Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

27 May 2018

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

27 May 2018

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The abscopal effect associated with a systemic anti-melanoma immune response

27 May 2018

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The three main stumbling blocks for anticancer T cells

27 May 2018

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27 May 2018

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Immunologic correlates of the abscopal effect in a patient with melanoma

27 May 2018

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Maximizing tumor immunity with fractionated radiation

27 May 2018

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Cancer immunotherapy comes of age

27 May 2018

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γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo

27 May 2018

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In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a phase 1/2 study

27 May 2018

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Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas

27 May 2018

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

27 May 2018

1 reference

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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

27 May 2018

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

27 May 2018

1 reference

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The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

27 May 2018

1 reference

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Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

27 May 2018

1 reference

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Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

27 May 2018

1 reference

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Immune responses to malignancies

27 May 2018

1 reference

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Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Combined IFN-gamma-endostatin gene therapy and radiotherapy attenuates primary breast tumor growth and lung metastases via enhanced CTL and NK cell activation and attenuated tumor angiogenesis in a murine model.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Invariant natural killer T cells regulate breast cancer response to radiation and CTLA-4 blockade

27 May 2018

1 reference

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

27 May 2018

1 reference

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Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

27 May 2018

1 reference

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Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

27 May 2018

1 reference

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Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity

27 May 2018

1 reference

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2. Dendritic cells as regulators of immunity and tolerance

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

27 May 2018

1 reference

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Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

The testis in immune privilege

27 May 2018

1 reference

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CNS immune privilege: hiding in plain sight

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

The consensus coding sequences of human breast and colorectal cancers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Cancer regression in patients after transfer of genetically engineered lymphocytes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Does the immune system see tumors as foreign or self?

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Cancer immunoediting: from immunosurveillance to tumor escape

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Tumour escape from immune surveillance through dendritic cell inactivation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Activation and inhibition of lymphocytes by costimulation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Immunosuppression in irradiated breast cancer patients: in vitro effect of cyclooxygenase inhibitors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

The effects of therapeutic irradiation on lymphocytes and immunity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Abscopal effect of radiation in papillary adenocarcinoma.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Depression of lymphocyte replicating ability in radiotherapy patients

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Systemic delivery of a TLR7 agonist in combination with radiation primes durable antitumor immune responses in mouse models of lymphoma

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Phase 1 study of stereotactic body radiotherapy and interleukin-2--tumor and immunological responses

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Epitope landscape in breast and colorectal cancer.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Radiation abscopal antitumor effect is mediated through p53

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Enhanced therapeutic effect of multiple injections of HSV-TK + GCV gene therapy in combination with ionizing radiation in a mouse mammary tumor model

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101987

Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

1 December 2018

1 reference

12 December 2020

Immunogenic tumor cell death induced by chemoradiotherapy in patients with esophageal squamous cell carcinoma

1 reference

12 December 2020

Effect of radiation therapy and in vitro x-ray exposure on lymphocyte subpopulations and their functions

1 reference

12 December 2020

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

1 reference

12 December 2020

Whole body irradiation; radiobiology or medicine?

1 reference

12 December 2020

Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI69219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863633%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863633%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23863633

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863633%20AND%20SRC:MED&resulttype=core&format=json