Pink1, the first ubiquitin kinase (Q42716362)

5 November 2017

Pink1, the first ubiquitin kinase (English)

1 reference

5 November 2017

Xinde Zheng

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5 November 2017

Tony Hunter

series ordinal

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5 November 2017

language of work or name

English

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publication date

18 June 2014

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5 November 2017

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5 November 2017

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5 November 2017

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5 November 2017

1621-1623

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Ubiquitin is phosphorylated by PINK1 to activate parkin

5 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Structure of the human Parkin ligase domain in an autoinhibited state

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Structure of parkin reveals mechanisms for ubiquitin ligase activation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

Autoregulation of Parkin activity through its ubiquitin-like domain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4194096

27 May 2018

Identifiers

DOI

10.15252/EMBJ.201489185

1 reference

5 November 2017

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5 November 2017

PubMed publication ID

24942162

1 reference