A relA/spoT homologous gene from Streptomyces coelicolor A3(2) controls antibiotic biosynthetic genes (Q42630092)

4 November 2017

title

A relA/spoT homologous gene from Streptomyces coelicolor A3(2) controls antibiotic biosynthetic genes (English)

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4 November 2017

main subject

Streptomyces parvulus

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Streptomyces coelicolor

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Streptomyces lividans

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Streptomyces albidoflavus

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Streptomyces werraensis

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Streptomyces avermitilis

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Streptomyces hiroshimensis

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(2Z,5Z)-3-methoxy-5-pyrrol-2-ylidene-2-[(5-undecyl-1H-pyrrol-2-yl)methylidene]pyrrole

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Streptomyces anthocyanicus

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Martínez-Costa OH

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4 November 2017

Arias P

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4 November 2017

Romero NM

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4 November 2017

Parro V

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4 November 2017

Mellado RP

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4 November 2017

Malpartida F

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4 November 2017

language of work or name

English

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publication date

1 May 1996

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Journal of Biological Chemistry

4 November 2017

published in

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4 November 2017

volume

271

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4 November 2017

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4 November 2017

page(s)

10627-10634

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Multilevel regulation of Streptomyces differentiation

4 November 2017

cites work

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The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces

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Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation

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A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp

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A cloned regulatory gene of Streptomyces lividans can suppress the pigment deficiency phenotype of different developmental mutants

21 January 2018

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Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2).

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A Morphological and Genetic Mapping Study of Bald Colony Mutants of Streptomyces coelicolor

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New loci required for Streptomyces coelicolor morphological and physiological differentiation

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Pleiotropic morphological and antibiotic deficiencies result from mutations in a gene encoding a tRNA-like product in Streptomyces coelicolor A3(2).

21 January 2018

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TTA codons in some genes prevent their expression in a class of developmental, antibiotic-negative, Streptomyces mutants

21 January 2018

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Carbon starvation and growth rate-dependent regulation of the Escherichia coli ribosomal RNA promoters: differential control of dual promoters

21 January 2018

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Basal ppGpp level adjustment shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coli

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Localization of the stringent protein of Escherichia coli on the 50S ribosomal subunit

21 January 2018

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A relaxed (rel) mutant of Streptomyces coelicolor A3(2) with a missing ribosomal protein lacks the ability to accumulate ppGpp, A-factor and prodigiosin.

21 January 2018

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Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor

21 January 2018

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Pleiotropic effects of a relC mutation in Streptomyces antibioticus

21 January 2018

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Activation of ATP:GTP 3'-pyrophosphotransferase (guanosine pentaphosphate synthetase) in Streptomyces antibioticus

21 January 2018

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Purification and properties of ATP:GTP 3'-pyrophosphotransferase (guanosine pentaphosphate synthetase) from Streptomyces antibioticus

21 January 2018

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

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The expression of Streptomyces and Escherichist coli drug-resistance determinants cloned into the Streptomyces phage φC31

21 January 2018

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Derivatives of pUC18 that have BglII sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening of Escherichia coli colonies

21 January 2018

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Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives

21 January 2018

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Construction and characterization of new cloning vehicles VI. Plasmid pBR329, a new derivative of pBR328 lacking the 482-base-pair inverted duplication

21 January 2018

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Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

The Streptomyces plasmid SCP2*: its functional analysis and development into useful cloning vectors.

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

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21 January 2018

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Codon usage in the G+C-rich Streptomyces genome

21 January 2018

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Mutational cloning in Streptomyces and the isolation of antibiotic production genes

21 January 2018

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21 January 2018

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21 January 2018

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Accumulation of bldA-specified tRNA is temporally regulated in Streptomyces coelicolor A3(2).

21 January 2018

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21 January 2018

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afsR2: a previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans

21 January 2018

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Stringent control during carbon starvation of marine Vibrio sp. strain S14: molecular cloning, nucleotide sequence, and deletion of the relA gene

21 January 2018

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Whole-genome random sequencing and assembly of Haemophilus influenzae Rd

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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GTP-binding domain: three consensus sequence elements with distinct spacing

21 January 2018

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A model for the tertiary structure of p21, the product of the ras oncogene.

21 January 2018

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Isolation of ras GTP-binding mutants using an in situ colony-binding assay

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Identification of Streptomyces coelicolor genes involved in regulation of antibiotic synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Streptomyces relC mutants with an altered ribosomal protein ST-L11 and genetic analysis of a Streptomyces griseus relC mutant

21 January 2018

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The stringent response in Streptomyces coelicolor A3(2)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Stringent response and initiation of secondary metabolism in Streptomyces clavuligerus.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

The Leeuwenhoek lecture, 1987. Towards an understanding of gene switching in Streptomyces, the basis of sporulation and antibiotic production.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

A Pigmented Mycelial Antibiotic in Streptomyces coelicolor: Control by a Chromosomal Gene Cluster

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Identification of the antibiotic determined by the SCP1 plasmid of Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

A New Channel-forming Antibiotic from Streptomyces coelicolor A3(2) Which Requires Calcium for its Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

A relaxed mutant with an altered ribosomal protein L11

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Occurrence of the stringent response in Streptomyces sp. and its significance for the initiation of morphological and physiological differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Initiation of antibiotic production by the stringent response of Bacillus subtilis Marburg

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Cloning and expression in a heterologous host of the complete set of genes for biosynthesis of the Streptomyces coelicolor antibiotic undecylprodigiosin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Plasmids, recombination and chromosome mapping in Streptomyces lividans 66

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Use of sodium trichloroacetate and mung bean nuclease to increase sensitivity and precision during transcript mapping

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

CDA is a new chromosomally-determined antibiotic from Streptomyces coelicolor A3(2)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

A procedure for the rapid preparation of guanosine tetraphosphate (ppGpp) from Escherichia coli ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

Effect of Serine Hydroxamate and Methyl a-D-glucopyranoside Treatment on Nucleoside Polyphosphate Pools, RNA and Protein Accumulation in Streptomyces hygroscopicus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10627

A decrease in GTP content is associated with aerial mycelium formation in Streptomyces MA406-A-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.18.10627

1 reference

4 November 2017

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