Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist (Q42540355)

https://doi.org/10.1016/j.jbc.2024.107597

2 November 2017

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11 October 2024

title

Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist (English)

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G protein-coupled receptor

2 November 2017

main subject

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2 November 2017

Lee MJ

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2 November 2017

Thangada S

series ordinal

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2 November 2017

Liu CH

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2 November 2017

Thompson BD

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2 November 2017

language of work or name

English

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publication date

1 August 1998

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Journal of Biological Chemistry

2 November 2017

published in

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2 November 2017

volume

273

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2 November 2017

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2 November 2017

page(s)

22105-22112

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The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway

2 November 2017

cites work

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Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

21 January 2018

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Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

21 January 2018

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 January 2018

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Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness

21 January 2018

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Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

21 January 2018

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The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

21 January 2018

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Signalling properties of lysophosphatidic acid.

21 January 2018

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LPA: a novel lipid mediator with diverse biological actions

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

21 January 2018

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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

21 January 2018

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Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D.

21 January 2018

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Lysophosphatidic acid: G-protein signalling and cellular responses

21 January 2018

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Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

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G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

21 January 2018

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The G-protein G13 but Not G12 Mediates Signaling from Lysophosphatidic Acid Receptor via Epidermal Growth Factor Receptor to Rho

21 January 2018

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Edg-2/Vzg-1 Couples to the Yeast Pheromone Response Pathway Selectively in Response to Lysophosphatidic Acid

21 January 2018

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Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

21 January 2018

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The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

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Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

21 January 2018

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

21 January 2018

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Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

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Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product

21 January 2018

1 reference

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Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid

21 January 2018

1 reference

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Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.34.22105

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2 November 2017

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