Ghrelin and its unacylated isoform stimulate the growth of adrenocortical tumor cells via an anti-apoptotic pathway (Q42510580)

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title

Ghrelin and its unacylated isoform stimulate the growth of adrenocortical tumor cells via an anti-apoptotic pathway (English)

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Delhanty PJ

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van Koetsveld PM

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Gauna C

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van de Zande B

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Vitale G

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Hofland LJ

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van der Lely AJ

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publication date

3 April 2007

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American Journal of Physiology - Endocrinology and Metabolism

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published in

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volume

293

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page(s)

E302-9

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Ghrelin and growth hormone secretagogue receptor are expressed in the rat adrenal cortex: Evidence that ghrelin stimulates the growth, but not the secretory activity of adrenal cells

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cites work

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Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a

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Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes

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Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor

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Circulating ghrelin levels and central ghrelin receptor expression are elevated in response to food deprivation in a seasonal mammal (Phodopus sungorus).

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Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin

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IFN-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro

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10.1152/AJPENDO.00377.2006

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Identifiers

DOI

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1 November 2017

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