Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways (Q42506345)

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English	Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways	scientific article

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scholarly article

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Europe PubMed Central

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1 November 2017

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways (English)

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1 November 2017

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J S Park

1

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L Qiao

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Z Z Su

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D Hinman

4

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K Willoughby

5

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R McKinstry

6

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A Yacoub

7

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G J Duigou

8

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C S Young

9

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S Grant

10

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M P Hagan

11

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E Ellis

12

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P B Fisher

13

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P Dent

14

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1 November 2017

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1 May 2001

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20

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25

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3266-3280

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1 November 2017

Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

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The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes

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The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation

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Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas

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Molecular themes in oncogenesis

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Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells

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Functional interaction between c-Jun and promoter factor Sp1 in epidermal growth factor-induced gene expression of human 12(S)-lipoxygenase

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Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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EGF receptor phosphorylation is affected by ionizing radiation

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RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.

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Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest

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Reciprocal subtraction differential RNA display: an efficient and rapid procedure for isolating differentially expressed gene sequences

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Long-term survival of glioblastoma multiforme: importance of histopathological reevaluation.

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The oestrogen-like effect of 4-hydroxytamoxifen on induction of transforming growth factor alpha mRNA in MDA-MB-231 breast cancer cells stably expressing the oestrogen receptor

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HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR

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Roles for basal and stimulated p21(Cip-1/WAF1/MDA6) expression and mitogen-activated protein kinase signaling in radiation-induced cell cycle checkpoint control in carcinoma cells

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A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes

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Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells.Miko

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Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

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Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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Expression of oestrogen receptor and transforming growth factor-alpha in MCF-7 cells after exposure to fractionated irradiation

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Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

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Subtraction hybridization identifies a transformation progression-associated gene PEG -3 with sequence homology to a growth arrest and DNA damage-inducible gene

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PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis

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Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells

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21 January 2018

The multistep nature of cancer

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21 January 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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21 January 2018

Autocrine regulation of membrane transforming growth factor-alpha cleavage

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7 January 2021

based on heuristic

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EPAS1 trans-activation during hypoxia requires p42/p44 MAPK

1 reference

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7 January 2021

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Antisense raf oligodeoxyribonucleotide is a radiosensitizer in vivo

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Calcium-dependent stimulation of mitogen-activated protein kinase activity in A431 cells by low doses of ionizing radiation.

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based on heuristic

inferred from DOI database lookup

Signaling angiogenesis via p42/p44 MAP kinase cascade

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7 January 2021

based on heuristic

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Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke

1 reference

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Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells

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7 January 2021

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inferred from DOI database lookup

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10.1038/SJ.ONC.1204258

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Europe PubMed Central

PubMed publication ID

1 November 2017

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PubMed publication ID

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Europe PubMed Central

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1 November 2017

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