islet amyloid polypeptide (Q424643)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P10997

Calcitonin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calcitonin peptide-like family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signaling receptor binding

identical protein binding

A hIAPP-derived all-D-amino-acid inhibits hIAPP fibrillation efficiently at membrane surface by targeting α-helical oligomeric intermediates

4 references

9 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

9 May 2017

Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

9 May 2017

Porcine islet amyloid polypeptide fragments are refractory to amyloid formation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

amyloid-beta binding

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

protein binding

1 reference

8 April 2019

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

identical protein binding

5 references

8 April 2019

Fiber-dependent amyloid formation as catalysis of an existing reaction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

8 April 2019

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

8 April 2019

Porcine islet amyloid polypeptide fragments are refractory to amyloid formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

8 April 2019

A hIAPP-derived all-D-amino-acid inhibits hIAPP fibrillation efficiently at membrane surface by targeting α-helical oligomeric intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

8 April 2019

Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

cell component

extracellular region

neuronal cell body

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

extracellular space

1 reference

9 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

inclusion body

1 reference

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

negative regulation of cell differentiation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

cell-cell signaling

1 reference

8 April 2019

Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

eating behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

signal transduction

1 reference

8 April 2019

An amylin receptor is revealed following co-transfection of a calcitonin receptor with receptor activity modifying proteins-1 or -3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

negative regulation of bone resorption

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

apoptotic process

1 reference

8 April 2019

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

negative regulation of cell population proliferation

1 reference

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

protein destabilization

1 reference

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

protein homooligomerization

1 reference

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

amyloid fibril formation

1 reference

9 May 2017

Antimicrobial activity of human islet amyloid polypeptides: an insight into amyloid peptides' connection with antimicrobial peptides

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10997

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

1 reference

8 April 2019

adenylate cyclase-activating G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

1 reference

8 April 2019

positive regulation of cytosolic calcium ion concentration

ISS

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

positive regulation of protein kinase A signaling

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

negative regulation of mitochondrion organization

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

negative regulation of protein homooligomerization

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

positive regulation of apoptotic process

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

positive regulation of MAPK cascade

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

protein homooligomerization

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

positive regulation of protein kinase B signaling

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

negative regulation of amyloid fibril formation

1 reference

8 April 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10997

http://purl.uniprot.org/uniprot/P10997

Gene Atlas image

PBB GE IAPP 207062 at fs.png
732 × 530; 8 KB

0 references

exact match

1 reference

Calcitonin, conserved site

Identifiers.org

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P10997

Calcitonin peptide-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P10997

Identifiers

MeSH descriptor ID

D058228

subject named as

Islet Amyloid Polypeptide

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1 reference

30 May 2020

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30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

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5 August 2016

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5 August 2016

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5 August 2016

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5 August 2016

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5 August 2016

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5 August 2016

1 reference

5 August 2016