Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice (Q42440126)

From Wikidata

Jump to navigation Jump to search

scientific article published on April 21, 2003

Language	Label	Description	Also known as
English	Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice	scientific article published on April 21, 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice (English)

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

author name string

Bing Zheng

2

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Xu Shi-wen

4

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Ivan Fisher

6

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Konstantinos Lazaridis

7

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Benoit de Crombrugghe

10

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Christopher P. Denton

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

Lowri A. Evans

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

Voon H. Ong

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

David J. Abraham

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

Carol M. Black

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

language of work or name

0 references

publication date

21 April 2003

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

full work available at URL

http://www.jbc.org/article/S0021925820869762/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707256

26 December 2023

https://api.elsevier.com/content/article/PII:S0021925820869762?httpAccept=text/xml

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

https://api.elsevier.com/content/article/PII:S0021925820869762?httpAccept=text/plain

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

https://syndication.highwire.org/content/doi/10.1074/jbc.M300636200

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

27

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

25109-25119

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Biology of TGF-beta in knockout and transgenic mouse models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Making sense of latent TGFbeta activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Transcriptional control of the mouse alpha 2(I) collagen gene: functional deletion analysis of the promoter and evidence for cell-specific expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

The dopamine β-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Biomedical discovery with DNA arrays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Endoglin expression on human microvascular endothelial cells association with betaglycan and formation of higher order complexes with TGF-beta signalling receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Loss of TGF-beta signaling contributes to autoimmune pancreatitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Absence of proximal duct apoptosis in the ventral prostate of transgenic mice carrying the C3(1)-TGF-beta type II dominant negative receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Regulation of transforming growth factor-beta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Deficient Smad7 expression: a putative molecular defect in scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Cytokine directed therapy in scleroderma: rationale, current status, and the future

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Increased transcriptional activities of transforming growth factor beta receptors in scleroderma fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Dysregulation of transforming growth factor beta signaling in scleroderma: overexpression of endoglin in cutaneous scleroderma fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

The heart and pulmonary vasculature in scleroderma: clinical features and pathobiology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

A simple, rapid, and sensitive DNA assay procedure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Activation of a fibroblast-specific enhancer of the proalpha2(I) collagen gene in tight-skin mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Does the triple helical domain of type I collagen encode molecular recognition and fiber assembly while telopeptides serve as catalytic domains? Effect of proteolytic cleavage on fibrillogenesis and on collagen-collagen interaction in fibers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Expression of TGF-beta 1, -beta 2 and -beta 3 in localized and systemic scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Mutations of bone morphogenetic protein receptor type II are not found in patients with pulmonary hypertension and underlying connective tissue diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300636200

21 January 2018

Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase

6

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

10

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Cancer Research

28

59

2861

author name string

Go

publication date

1999

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice

38

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

American Journal of Physiology

40

284

G525

author name string

Schramm

publication date

2003

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

44

1 reference

10.1074/JBC.M300636200

https://api.crossref.org/works/10.1074/JBC.M300636200

26 December 2023

Identifiers

10.1074/JBC.M300636200

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42440126&oldid=2037252492"