Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase (Q42433911)

31 October 2017

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase (English)

1 reference

31 October 2017

1 reference

31 October 2017

Chaitan Khosla

1 reference

31 October 2017

Alice Y Chen

1 reference

31 October 2017

Nathan A Schnarr

series ordinal

1 reference

31 October 2017

David E Cane

series ordinal

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31 October 2017

language of work or name

English

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publication date

1 March 2006

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Journal of the American Chemical Society

31 October 2017

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31 October 2017

128

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31 October 2017

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31 October 2017

3067-3074

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Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase

31 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Polyketide and nonribosomal peptide antibiotics: modularity and versatility

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Strategies for combinatorial biosynthesis with modular polyketide synthases.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Quantitative analysis of the relative contributions of donor acyl carrier proteins, acceptor ketosynthases, and linker regions to intermodular transfer of intermediates in hybrid polyketide synthases

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Polyketide biosynthesis: a millennium review

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Tolerance and specificity of polyketide synthases

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Post-translational modification of polyketide and nonribosomal peptide synthases

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Modular organization of genes required for complex polyketide biosynthesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Analysis of covalently bound polyketide intermediates on 6-deoxyerythronolide B synthase by tandem proteolysis-mass spectrometry

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Manipulation and analysis of polyketide synthases

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Precursor-directed biosynthesis: biochemical basis of the remarkable selectivity of the erythromycin polyketide synthase toward unsaturated triketides

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532788

PCR-mediated recombination and mutagenesis. SOEing together tailor-made genes

16 August 2018

1 reference

12 December 2020

Precursor-Directed Biosynthesis of Erythromycin Analogs by an Engineered Polyketide Synthase

1 reference

12 December 2020

Harnessing the biosynthetic code: combinations, permutations, and mutations

1 reference

12 December 2020

Dissecting and exploiting intermodular communication in polyketide synthases

1 reference

12 December 2020

Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA058093D

1 reference

release_ko2xhpnagjcbjmytvqy4mpec4u

31 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ko2xhpnagjcbjmytvqy4mpec4u

24 November 2022

mapped directly with Wikidata item

1 reference

31 October 2017

PubMed publication ID

16506788

1 reference