The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson's disease (Q42351555)

27 October 2017

The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson's disease (English)

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27 October 2017

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7 June 2020

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7 June 2020

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7 June 2020

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7 June 2020

Luca Biasetti

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7 June 2020

Ben J F Blakeman

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7 June 2020

Saskia J Pollack

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7 June 2020

Shahin Zibaee

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7 June 2020

Alaa Abdul-Sada

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7 June 2020

language of work or name

English

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publication date

16 December 2016

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27 October 2017

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7 June 2020

volume

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7 June 2020

page(s)

39171

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Creative Commons Attribution 4.0 International

7 June 2020

start time

1 December 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.

1 reference

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Structural disorder of monomeric α-synuclein persists in mammalian cells.

29 May 2018

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α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane

29 May 2018

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An imaging and systems modeling approach to fibril breakage enables prediction of amyloid behavior

29 May 2018

1 reference

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A central role for dityrosine crosslinking of Amyloid-β in Alzheimer's disease.

29 May 2018

1 reference

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The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1.

29 May 2018

1 reference

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Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals

29 May 2018

1 reference

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In vivo demonstration that alpha-synuclein oligomers are toxic

29 May 2018

1 reference

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Human beta-synuclein rendered fibrillogenic by designed mutations

29 May 2018

1 reference

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Evidence for copper-dioxygen reactivity during alpha-synuclein fibril formation.

29 May 2018

1 reference

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Unique copper-induced oligomers mediate alpha-synuclein toxicity

29 May 2018

1 reference

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Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance

29 May 2018

1 reference

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Alpha-Synuclein conformation affects its tyrosine-dependent oxidative aggregation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

The fold of alpha-synuclein fibrils

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Metals in Alzheimer's and Parkinson's diseases

29 May 2018

1 reference

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A three-stage kinetic model of amyloid fibrillation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

The aggregation and fibrillation of alpha-synuclein

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Alpha-synuclein and neurodegenerative diseases

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

The application of LR gold resin for immunogold labeling

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure

29 May 2018

1 reference

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Quantum dots as ultrasensitive nanoactuators and sensors of amyloid aggregation in live cells

17 August 2018

1 reference

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Cysteine misincorporation in bacterially expressed human alpha-synuclein

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Conformational properties of alpha-synuclein in its free and lipid-associated states

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Immunochemical detection of protein dityrosine in atherosclerotic lesion of apo-E-deficient mice using a novel monoclonal antibody.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5159849

[34] X-Ray fiber diffraction of amyloid fibrils

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP39171

Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments

21 January 2018

1 reference

12 December 2020

Epidemiology of Parkinson's disease.

1 reference

12 December 2020

Raised cerebrospinal-fluid copper concentration in Parkinson's disease

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP39171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27982082%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27982082%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

27982082

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27982082%20AND%20SRC:MED&resulttype=core&format=json