BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity (Q42280757)

19 October 2017

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity (English)

1 reference

19 October 2017

1 reference

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6 June 2020

1 reference

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6 June 2020

1 reference

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6 June 2020

1 reference

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6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729482%20AND%20SRC:MED&resulttype=core&format=json

Bernardo Reina San-Martin

6 June 2020

1 reference

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6 June 2020

1 reference

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6 June 2020

1 reference

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6 June 2020

Xianning Lai

1 reference

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6 June 2020

Cecilia Folio

1 reference

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6 June 2020

Gijs Zonderland

1 reference

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6 June 2020

Sophie Badie

1 reference

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6 June 2020

Johanna Michl

1 reference

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6 June 2020

Irene Sechi

1 reference

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6 June 2020

Mélanie Rogier

1 reference

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6 June 2020

Verónica Matía García

1 reference

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6 June 2020

Ankita Sati Batra

1 reference

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6 June 2020

Oscar M Rueda

1 reference

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6 June 2020

Joannie Hui

1 reference

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6 June 2020

Nelson Tang

1 reference

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6 June 2020

Alejandra Bruna

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6 June 2020

publication date

20 July 2017

1 reference

19 October 2017

EMBO Molecular Medicine

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6 June 2020

volume

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6 June 2020

issue

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6 June 2020

page(s)

1398-1414

1 reference

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describes a project that uses

6 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5623864/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.

26 October 2017

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26 October 2017

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26 October 2017

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Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis

26 October 2017

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Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

26 October 2017

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ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets

26 October 2017

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Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study

26 October 2017

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

26 October 2017

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26 October 2017

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Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer

26 October 2017

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Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors

26 October 2017

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Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

26 October 2017

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A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

26 October 2017

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26 October 2017

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BRCA1 and BRCA2: different roles in a common pathway of genome protection

26 October 2017

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The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis.

26 October 2017

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth

26 October 2017

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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

26 October 2017

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

26 October 2017

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A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors

26 October 2017

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26 October 2017

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Molecular mechanisms of alcohol-mediated carcinogenesis

26 October 2017

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Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells

26 October 2017

1 reference

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DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis

26 October 2017

1 reference

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

26 October 2017

1 reference

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5623864

Biallelic inactivation of BRCA2 in Fanconi anemia

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5623864

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

26 October 2017

1 reference

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Induction of senescence by oncogenic Ras.

26 October 2017

1 reference

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A third-generation lentivirus vector with a conditional packaging system

26 October 2017

1 reference

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

26 October 2017

1 reference

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Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals

26 October 2017

1 reference

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Oxidizing to death: disulfiram for cancer cell killing

26 October 2017

1 reference

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Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors.

17 August 2018

1 reference

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Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5623864

Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5623864

Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5623864

1 December 2018

Identifiers

DOI

10.15252/EMMM.201607446

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729482%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729482%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

28729482

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729482%20AND%20SRC:MED&resulttype=core&format=json