enalapril (Q422185)

N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-D-proline

enalapril (English)

3 October 2016

1 reference

based on heuristic

inferred from InChI

(2S)-1-((2S)-2-(((1R)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid

1 reference

based on heuristic

inferred from InChI

chemical formula

C₂₀H₂₈N₂O₅

1 reference

enalapril (English)

19 November 2016

CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O

1 reference

enalapril (English)

19 November 2016

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O

1 reference

enalapril (English)

19 November 2016

10 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C09AA02

10 milligram

route of administration

parenteral route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C09AA02

activator of

Col3a1

determination method or standard

EXP

Evidence & Conclusion Ontology ID

ECO_0007119

2 references

Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice

type of reference

review article

Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases.

1 reference

14 February 2018

1 reference

14 February 2018

World Health Organisation international non-proprietary name

enalapril (English)

2 references

medical condition treated

enalapril (English)

3 October 2016

Recommended INN: List 22

publication date

1982

1 reference

13 December 2016

malignant hypertension

1 reference

13 December 2016

1 reference

13 December 2016

arterial hypertension

1 reference

13 December 2016

1 reference

13 December 2016

congestive heart failure

1 reference

Food and Drug Administration

13 December 2016

arterial hypertension

start time

24 December 1985

approved by

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/69PN84IO1A

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/018998s080lbl.pdf

significant drug interaction

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

triamterene

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amiloride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

trimethoprim

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eplerenone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

spironolactone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eplerenone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bromocriptine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

spironolactone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bromocriptine

hyperinsulinism

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Sleep state misperception

1 reference

A reference set of clinically relevant adverse drug-drug interactions

irritability

1 reference

A reference set of clinically relevant adverse drug-drug interactions

delirium

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

orthostatic hypotension

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

orthostatic hypotension

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

angiotensin I converting enzyme

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6322

17 August 2016

legal status (medicine)

boxed warning

1 reference

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

LiverTox likelihood score

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Enalapril

11 February 2018

1 reference

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

D004656

15 March 2018

antihypertensive drug

1 reference

imported from Wikimedia project

Medical Subject Headings

15 March 2018

0 references

2933.99.46

0 references

0 references

0 references

0 references

Enalapril

0 references

Commons category

Enalapril

1 reference

Russian Wikipedia

topic's main category

Category:Enalapril

0 references

Identifiers

InChI

InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1

1 reference

enalapril (English)

19 November 2016

2 references

enalapril (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

75847-73-3

2 references

enalapril (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=75847-73-3

10 April 2021

1 reference

Enalapril (English)

19 November 2016

2 references

enalapril (English)

19 November 2016

40466924

1 reference

Reaxys registry number

3657467

1 reference

enalapril (English)

3 October 2016

mapping relation type

3 references

ENALAPRIL (English)

19 November 2016

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1

1 reference

ENALAPRIL (English)

19 November 2016

2 references

inferred from InChIKey

splash10-004i-0809000000-0e192d1573028e60641c

1 reference

MassBank accession ID

SM861601

0 references

SM861651

0 references

MSBNK-Waters-WA001937

0 references

MSBNK-Waters-WA001938

0 references

MSBNK-Waters-WA001939

0 references

MSBNK-Waters-WA001940

0 references

MSBNK-Waters-WA001941

0 references

SPLASH

0 references

HSDB ID

6529

1 reference

Hazardous Substances Data Bank

28 October 2019

Enalapril (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

ECHA Substance Infocard ID

100.119.661

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.119.661

27 December 2018

L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl- (English)

quotation

CAS no.: 75847-73-3 (English)

1 reference

World Health Organisation international non-proprietary name numeric ID

Enalapril (English)

publication date

17 November 2015

5117

1 reference

https://mednet-communities.net/inn/db/ViewINN.aspx?i=5117

Guide to Pharmacology Ligand ID

6322

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6322

enalapril (English)

19 November 2016

Enalapril

0 references

0 references

0 references

1 reference

enalapril (English)

19 November 2016

1 reference

Human Metabolome Database ID

HMDB0014722

2 references

based on heuristic

inferred from InChIKey

2 references

enalapril (English)

19 November 2016

MedlinePlus drug identifier

0 references

1 reference

enalapril (English)

19 November 2016

0 references

1 reference

1 reference

enalapril (English)

3 October 2016

1 reference

enalapril (English)

electronic Essential Medicines List medicine ID

3 October 2016

137

1 reference

https://list.essentialmeds.org/medicines/137

https://docs.openalex.org/download-snapshot/snapshot-data-format

eEML - Electronic Essential Medicines List (English)

23 October 2021

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0014025

1 reference

enalapril (English)

19 November 2016

0 references

WordNet 3.1 Synset ID

03290017-n

1 reference