Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex (Q42152403)

17 October 2017

title

Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex (English)

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17 October 2017

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William A Barton

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17 October 2017

Dorothea Tzvetkova-Robev

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17 October 2017

Edward P Miranda

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17 October 2017

Momchil V Kolev

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17 October 2017

Kanagalaghatta R Rajashankar

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17 October 2017

Juha P Himanen

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17 October 2017

Dimitar B Nikolov

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17 October 2017

language of work or name

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28 May 2006

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Nature Structural & Molecular Biology

17 October 2017

published in

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17 October 2017

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17 October 2017

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17 October 2017

page(s)

524-532

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Blood vessel formation: what is its molecular basis?

17 October 2017

cites work

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Vascular-specific growth factors and blood vessel formation

31 March 2020

1 reference

Tie receptors: new modulators of angiogenic and lymphangiogenic responses

31 March 2020

1 reference

Angiogenesis in cancer and other diseases

31 March 2020

1 reference

Vascular development: molecular logic for defining arteries and veins

31 March 2020

1 reference

Angiogenesis in ischemic and neoplastic disorders

31 March 2020

1 reference

Angiogenesis and tumor metastasis

31 March 2020

1 reference

Expression of angiopoietin-1, angiopoietin-2, and Tie2 genes in normal ovary with corpus luteum and in ovarian cancer

31 March 2020

1 reference

Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma

31 March 2020

1 reference

Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

31 March 2020

1 reference

Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis

31 March 2020

1 reference

Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

31 March 2020

1 reference

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

31 March 2020

1 reference

Getting Tie(2)d up in angiogenesis

31 March 2020

1 reference

Angiopoietins 3 and 4: diverging gene counterparts in mice and humans

31 March 2020

1 reference

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

31 March 2020

1 reference

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

31 March 2020

1 reference

Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats

31 March 2020

1 reference

Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition

31 March 2020

1 reference

Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

31 March 2020

1 reference

The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development.

31 March 2020

1 reference

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.

31 March 2020

1 reference

Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.

31 March 2020

1 reference

Protein tyrosine kinase structure and function

31 March 2020

1 reference

Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains

31 March 2020

1 reference

A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1

31 March 2020

1 reference

The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion

31 March 2020

1 reference

Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution

31 March 2020

1 reference

Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein

31 March 2020

1 reference

Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen

31 March 2020

1 reference

The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro

31 March 2020

1 reference

The CCP4 suite: programs for protein crystallography

31 March 2020

1 reference

Structural features of the reactions between antibodies and protein antigens.

31 March 2020

1 reference

Molecular recognition in antibody-antigen complexes

31 March 2020

1 reference

The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems

31 March 2020

1 reference

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

31 March 2020

1 reference

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

31 March 2020

1 reference

Direct cell adhesion to the angiopoietins mediated by integrins

31 March 2020

1 reference

Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor

31 March 2020

1 reference

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

31 March 2020

1 reference

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

31 March 2020

1 reference

Eph signaling: a structural view

31 March 2020

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

Triiodide derivatization and combinatorial counter-ion replacement: two methods for enhancing phasing signal using laboratory Cu Kα X-ray equipment

31 March 2020

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

31 March 2020

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB1101

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17 October 2017

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