Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. (Q42151361)

17 October 2017

Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. (English)

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Streptomyces clavuligerus

17 October 2017

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Streptomyces coelicolor

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Streptomyces flavovirens

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Streptomyces katsurahamanus

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Streptomyces flavogriseus

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Streptomyces albidoflavus

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Streptomyces jumonjinensis

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N-{4-oxo-5H-[1,2]dithiolo[3,4-b]pyrrol-3-yl}ethanimidic acid

1 reference

Hua Yin

1 reference

17 October 2017

Sihai Xiang

1 reference

17 October 2017

Jianting Zheng

1 reference

17 October 2017

Keqiang Fan

1 reference

17 October 2017

Tingting Yu

1 reference

17 October 2017

Xu Yang

1 reference

17 October 2017

Yanfeng Peng

1 reference

17 October 2017

Haibin Wang

1 reference

17 October 2017

Deqin Feng

1 reference

17 October 2017

Yuanming Luo

1 reference

17 October 2017

Hua Bai

1 reference

17 October 2017

Keqian Yang

1 reference

17 October 2017

language of work or name

English

0 references

publication date

17 February 2012

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full work available at URL

17 October 2017

https://aem.asm.org/content/aem/78/9/3431.full.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1128/aem.07699-11?email=unpaywall_01@example.com

published in

Applied and Environmental Microbiology

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17 October 2017

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17 October 2017

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17 October 2017

3431-3441

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https://api.unpaywall.org/v2/10.1128/aem.07699-11?email=unpaywall_01@example.com

17 October 2017

1 reference

19 March 2024

access restriction status

open access

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inferred from online access status

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Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus

29 May 2018

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Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways

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Antimicrobial properties and mode of action of the pyrrothine holomycin

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Characterization and expression of the arginine biosynthesis gene cluster of Streptomyces clavuligerus.

29 May 2018

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Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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Holomycin and an antibiotic(MM 19290) related to tunicamycin, metabolites of Streptomyces clavuligerus

29 May 2018

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A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production

29 May 2018

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Role of σ-factor (orf21) in clavulanic acid production in Streptomyces clavuligerus NRRL3585

17 August 2018

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Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield

17 August 2018

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Proline reduces the binding of transcriptional regulator ArgR to upstream of argB in Corynebacterium glutamicum.

17 August 2018

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Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

CymR, the master regulator of cysteine metabolism in Staphylococcus aureus, controls host sulphur source utilization and plays a role in biofilm formation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

A gene located downstream of the clavulanic acid gene cluster in Streptomyces clavuligerus ATCC 27064 encodes a putative response regulator that affects clavulanic acid production.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

ArgR-dependent repression of arginine and histidine transport genes in Escherichia coli K-12.

17 August 2018

1 reference

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A statistical approach using L(25) orthogonal array method to study fermentative production of clavulanic acid by Streptomyces clavuligerus MTCC 1142.

17 August 2018

1 reference

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5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus.

17 August 2018

1 reference

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Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus

17 August 2018

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Effect of amino acids containing sulfur on dithiolopyrrolone antibiotic productions by Saccharothrix algeriensis NRRL B-24137.

17 August 2018

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Construction of efficient conjugal plasmids between Escherichia coli and Streptomycetes

17 August 2018

1 reference

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Asymmetric allosteric activation of the symmetric ArgR hexamer

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

Arginine boxes and the argR gene in Streptomyces clavuligerus: evidence for a clear regulation of the arginine pathway

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

Possible involvement of the lysine epsilon-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346449

Naturally-occurring beta-lactamase inhibitors with antibacterial activity

17 August 2018

1 reference

12 December 2020

Characterization and complementation of a cephalosporin-deficient mutant of Streptomyces clavuligerus NRRL 3585

1 reference

12 December 2020

The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'super-cluster' in three Streptomyces

1 reference

12 December 2020

Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus

1 reference

12 December 2020

Identifiers

DOI

10.1128/AEM.07699-11

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

22344669

1 reference