Hedgehog targets in theDrosophilaembryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling (Q42086246)

16 October 2017

Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling (English)

1 reference

https://api.crossref.org/works/10.1242/DEV.055871

16 October 2017

Hedgehog targets in theDrosophilaembryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling (English)

1 reference

Cubitus interruptus Dmel_CG2125

10 August 2024

main subject

1 reference

GOA release 2020-03-11

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

10 August 2024

Brian Biehs

1 reference

16 October 2017

Katerina Kechris

series ordinal

1 reference

16 October 2017

Songmei Liu

series ordinal

1 reference

16 October 2017

Thomas B. Kornberg

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

10 August 2024

language of work or name

English

0 references

publication date

1 November 2010

1 reference

full work available at URL

16 October 2017

1 reference

inferred from page(s)

http://dev.biologists.org/content/137/22/3887.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20978080/?tool=EBI

10 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

http://dev.biologists.org/cgi/content/abstract/137/22/3887

10 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

https://europepmc.org/articles/PMC3049281

10 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

https://doi.org/10.1242/dev.055871

10 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20978080

http://journals.biologists.com/dev/article-pdf/137/22/3887/1203932/3887.pdf

10 August 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1242/DEV.055871

10 August 2024

1 reference

16 October 2017

137

1 reference

16 October 2017

1 reference

16 October 2017

3887-3898

1 reference

describes a project that uses

16 October 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3049281

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

30 May 2018

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A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

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Hedgehog: functions and mechanisms

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Hedgehog serves as a mitogen and survival factor during embryonic stem cell neurogenesis

30 May 2018

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Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

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High-throughput assay for determining specificity and affinity of protein-DNA binding interactions

30 May 2018

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Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo

30 May 2018

1 reference

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Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells

30 May 2018

1 reference

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Proximal genomic localization of STAT1 binding and regulated transcriptional activity

30 May 2018

1 reference

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Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

30 May 2018

1 reference

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Direct regulation of knot gene expression by Ultrabithorax and the evolution of cis-regulatory elements in Drosophila

30 May 2018

1 reference

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Cadherin Cad99C is regulated by Hedgehog signaling in Drosophila.

30 May 2018

1 reference

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Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

30 May 2018

1 reference

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Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

30 May 2018

1 reference

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Developmental roles and clinical significance of hedgehog signaling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Patched acts catalytically to suppress the activity of Smoothened

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Requirements of high levels of Hedgehog signaling activity for medial-region cell fate determination in Drosophila legs: identification of pxb, a putative Hedgehog signaling attenuator gene repressed along the anterior-posterior compartment boundary

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling

30 May 2018

1 reference

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Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo

30 May 2018

1 reference

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Controlling the false discovery rate in behavior genetics research

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Chromatin profiling using targeted DNA adenine methyltransferase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

An absolute requirement for Cubitus interruptus in Hedgehog signaling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Cubitus interruptus is necessary but not sufficient for direct activation of a wing-specific decapentaplegic enhancer.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Cluster analysis and display of genome-wide expression patterns

30 May 2018

1 reference

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Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

30 May 2018

1 reference

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Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein

30 May 2018

1 reference

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

30 May 2018

1 reference

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ladybird, a tandem of homeobox genes that maintain late wingless expression in terminal and dorsal epidermis of the Drosophila embryo.

30 May 2018

1 reference

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The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster

30 May 2018

1 reference

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araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing.

30 May 2018

1 reference

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

30 May 2018

1 reference

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Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Growth and differentiation in the Drosophila eye coordinated by hedgehog

30 May 2018

1 reference

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Double-label in situ hybridization using biotin and digoxigenin-tagged RNA probes.

30 May 2018

1 reference

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Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

30 May 2018

1 reference

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The function of engrailed and the specification of Drosophila wing pattern

30 May 2018

1 reference

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Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila

30 May 2018

1 reference

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The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched.

30 May 2018

1 reference

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Segment polarity genes and cell patterning within the Drosophila body segment

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Interaction between Ataxin-2 Binding Protein 1 and Cubitus-interruptus during wing development in Drosophila

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Linear RNA amplification for the production of microarray hybridization probes.

17 August 2018

1 reference

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A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Inducible production of interferon-gamma in the developing brain causes cerebellar dysplasia with activation of the Sonic hedgehog pathway.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Mechanism of hedgehog signaling during Drosophila eye development

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Heart tube patterning in Drosophila requires integration of axial and segmental information provided by the Bithorax Complex genes and hedgehog signaling

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Dpp and Hh signaling in the Drosophila embryonic eye field.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog signaling patterns the tracheal branches

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

DWnt-4 and Wingless have distinct activities in the Drosophila dorsal epidermis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Tissue-specific regulation of cyclin E transcription during Drosophila melanogaster embryogenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Drosophila segment borders result from unilateral repression of hedgehog activity by wingless signaling.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Cross-regulatory interactions among tracheal genes support a co-operative model for the induction of tracheal fates in the Drosophila embryo.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Patterning of Drosophila leg sensory organs through combinatorial signaling by hedgehog, decapentaplegic and wingless.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog activates the EGF receptor pathway during Drosophila head development.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Segmentation and specification of the Drosophila mesoderm.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049281

Genetic analysis of hedgehog signalling in the Drosophila embryo

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/DEV.055871

1 reference

16 October 2017

1 reference

16 October 2017

1 reference