Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds. (Q41988339)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20853839%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds (English)

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14 February 2020

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14 February 2020

Michelle A O'Malley

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14 February 2020

Andrea N Naranjo

series ordinal

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14 February 2020

Tzvetana Lazarova

series ordinal

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14 February 2020

language of work or name

English

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publication date

1 November 2010

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14 February 2020

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14 February 2020

volume

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14 February 2020

issue

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14 February 2020

page(s)

9181-9189

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Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

14 February 2020

cites work

1 reference

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Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists

5 June 2018

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Progress toward heterologous expression of active G-protein-coupled receptors in Saccharomyces cerevisiae: Linking cellular stress response with translocation and trafficking

5 June 2018

1 reference

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Methods for measuring the thermodynamic stability of membrane proteins.

5 June 2018

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

5 June 2018

1 reference

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Over-expression, solubilization, and purification of G protein-coupled receptors for structural biology

5 June 2018

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

5 June 2018

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The protein folding problem

5 June 2018

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A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists

5 June 2018

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Structural diversity of G protein-coupled receptors and significance for drug discovery

5 June 2018

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Microscale fluorescent thermal stability assay for membrane proteins

5 June 2018

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New G-protein-coupled receptor crystal structures: insights and limitations

5 June 2018

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

5 June 2018

1 reference

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Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics.

5 June 2018

1 reference

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High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor

5 June 2018

1 reference

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Membrane proteins shape up: understanding in vitro folding.

5 June 2018

1 reference

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Solving the membrane protein folding problem

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Decreases in yeast expression yields of the human adenosine A2a receptor are a result of translational or post-translational events.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Identification of core amino acids stabilizing rhodopsin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Structure-based analysis of GPCR function: conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Stability of membrane proteins: relevance for the selection of appropriate methods for high-resolution structure determinations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Crystal structure of rhodopsin: A G protein-coupled receptor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Disulfide bonds and protein folding.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

A method for assessing the stability of a membrane protein.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Mutagenic analysis of platelet thromboxane receptor cysteines. Roles in ligand binding and receptor-effector coupling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Engineered disulfide bonds as probes of the folding pathway of barnase: increasing the stability of proteins against the rate of denaturation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Nomenclature and classification of purinoceptors.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Forces and factors that contribute to the structural stability of membrane proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Structure and stability of membrane proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain

5 June 2018

1 reference

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5 June 2018

Quantitation of protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Adenosine A1 and A2 receptors: structure--function relationships

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

An adrenaline (and gold?) rush for the GPCR community

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

How aggregation and conformational scrambling of unfolded states govern fluorescence emission spectra

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Co-expression of molecular chaperones does not improve the heterologous expression of mammalian G-protein coupled receptor expression in yeast

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Conformation and stability of alpha-helical membrane proteins. 2. Influence of pH and salts on stability and unfolding of rhodopsin

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Mutation of human mu opioid receptor extracellular "disulfide cysteine" residues alters ligand binding but does not prevent receptor targeting to the cell plasma membrane

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964423

Pharmacological characterization of the rat A2a adenosine receptor functionally coupled to the yeast pheromone response pathway

18 August 2018

1 reference

12 December 2020

A carboxyl-terminally truncated mutant and nonglycosylated A2a adenosine receptors retain ligand binding

1 reference

12 December 2020

Inactivation of the beta-adrenergic receptor in cardiac muscle by dithiols

1 reference

12 December 2020

Aggregation Behavior of Sugar Surfactants in Aqueous Solutions: Effects of Temperature and the Addition of Nonionic Polymers

1 reference

12 December 2020

Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor

1 reference

12 December 2020

Membrane protein folding and oligomerization: the two-stage model

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI101155R

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20853839%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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14 February 2020

PubMed publication ID

20853839

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20853839%20AND%20SRC:MED&resulttype=core&format=json