TREK-1, a K+ channel involved in polymodal pain perception (Q41962937)

14 October 2017

TREK-1, a K+ channel involved in polymodal pain perception (English)

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14 October 2017

1 reference

14 October 2017

Katharina Zimmermann

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Marc Borsotto

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Fabrice Duprat

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Jean Chemin

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Peter Reeh

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Abdelkrim Alloui

1 reference

14 October 2017

Julien Mamet

1 reference

14 October 2017

Jacques Noël

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14 October 2017

Nicolas Guy

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14 October 2017

Nicolas Voilley

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14 October 2017

Catherine Rubat-Coudert

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14 October 2017

Georges Romey

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14 October 2017

Catherine Heurteaux

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14 October 2017

Alain Eschalier

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14 October 2017

Michel Lazdunski

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14 October 2017

language of work or name

English

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publication date

4 May 2006

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14 October 2017

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14 October 2017

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14 October 2017

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14 October 2017

2368-2376

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Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Voltage-gated sodium channels and pain pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

TREK-1, a K+ channel involved in neuroprotection and general anesthesia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Abnormal osmotic regulation in trpv4 -/- mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

The inhibitory effect of fentanyl and other morphine-like analgesics on the warm water induced tail withdrawl reflex in rats

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

The TRPV4 channel: structure-function relationship and promiscuous gating behaviour.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Specificity of cold thermotransduction is determined by differential ionic channel expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Molecular mechanisms of nociception

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Lipid and mechano-gated 2P domain K(+) channels.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

TREK-1 is a heat-activated background K(+) channel

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Axonal transport of TREK and TRAAK potassium channels in rat sciatic nerves

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Neuropathic pain: aetiology, symptoms, mechanisms, and management

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

A capsaicin-receptor homologue with a high threshold for noxious heat

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Ion channels of nociception.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

The cloned capsaicin receptor integrates multiple pain-producing stimuli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

A mammalian two pore domain mechano-gated S-like K+ channel

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

The capsaicin receptor: a heat-activated ion channel in the pain pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Sensory receptors in mammalian skin in an in vitro preparation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Rat knee-joint carrageenin incapacitation test: an objective screen for central and peripheral analgesics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

TREK-2 (K2P10.1) and TRESK (K2P18.1) are major background K+ channels in dorsal root ganglion neurons

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Histamine activates a background, arachidonic acid-sensitive K channel in embryonic chick dorsal root ganglion neurons.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Hypotonicity induces TRPV4-mediated nociception in rat.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Heat-evoked activation of the ion channel, TRPV4.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

TASK-3 dominates the background potassium conductance in rat adrenal glomerulosa cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Influence of thermode size for detecting heat pain dysfunction in a capsaicin model of epidermal nerve fiber loss

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Behavioural measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478167

Neuropathic pain sensations are differentially sensitive to dextrorphan

18 August 2018

1 reference

12 December 2020

Multiple subtypes of serotonin receptors are expressed in rat sensory neurons in culture

1 reference

12 December 2020

A method for evaluating both non-narcotic and narcotic analgesics

1 reference

12 December 2020

A method for measurement of analgesic activity on inflamed tissue

1 reference

12 December 2020

Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses

1 reference

12 December 2020

Specific Involvement of PKC-ε in Sensitization of the Neuronal Response to Painful Heat

1 reference

12 December 2020

Methodological refinements to the mouse paw formalin test. An animal model of tonic pain

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601116

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

16675954

1 reference