Distribution of mutations around rearranged heavy-chain antibody variable-region genes (Q41966971)

14 October 2017

Distribution of mutations around rearranged heavy-chain antibody variable-region genes (English)

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14 October 2017

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Both GW

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14 October 2017

Taylor L

series ordinal

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14 October 2017

Pollard JW

series ordinal

1 reference

14 October 2017

Steele EJ

series ordinal

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14 October 2017

language of work or name

English

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publication date

1 October 1990

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Molecular and Cellular Biology

14 October 2017

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14 October 2017

1 reference

14 October 2017

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14 October 2017

5187-5196

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Somatic mutation of immunoglobulin light-chain variable-region genes

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Serotype-specific glycoprotein of simian 11 rotavirus: coding assignment and gene sequence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Clusters of point mutations are found exclusively around rearranged antibody variable genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Antibody diversity: somatic hypermutation of rearranged VH genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Molecular basis of an isogeneic anti-idiotypic response.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Somatic mutation and clonal expansion of B cells in an antigen-driven immune response.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Patterns of somatic mutations in immunoglobulin variable genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Antibody engineering for the analysis of affinity maturation of an anti-hapten response.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Mutational analysis of the immunoglobulin heavy chain promoter region

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Palindromic sequences are associated with sites of DNA breakage during gene conversion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Fowlpox virus thymidine kinase: nucleotide sequence and relationships to other thymidine kinases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Exonucleolytic proofreading

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Might gene conversion be the mechanism of somatic hypermutation of mammalian immunoglobulin genes?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Fidelity of DNA polymerases in DNA amplification

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Retroviral vector system for the study of cDNA gene formation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

DNA sequencing with chain-terminating inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Somatic mutations of immunoglobulin variable genes are restricted to the rearranged V gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361197

Origin of Antibody Variation

18 August 2018

1 reference

12 December 2020

Genetic noise in evolution?

1 reference

12 December 2020

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1 reference

12 December 2020

V gene rearrangement is required to fully activate the hypermutation mechanism in B cells

1 reference

12 December 2020

Mechanism of antigen-driven selection in germinal centres

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.10.10.5187

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

2118991

1 reference